Commission Implementing Regulation (EU) 2022/1434 of 22 July 2022 granting a Union authorisation for the biocidal product family CMIT-MIT Aqueous 1.5-15Text with EEA relevance

Commission Implementing Regulation (EU) 2022/1434 of 22 July 2022 granting a Union authorisation for the biocidal product family CMIT-MIT Aqueous 1.5-15 (Text with EEA relevance) THE EUROPEAN COMMISSION, Having regard to the Treaty on the Functioning of the European Union, Having regard to Regulation (EU) No 528/2012 of the European Parliament and of the Council of 22 May 2012 concerning the making available on the market and use of biocidal products OJ L 167, 27.6.2012, p. 1. , and in particular the first subparagraph of Article 44(5) thereof, Whereas: (1) On 21 June 2017, Nutrition & Biosciences Netherlands B.V. submitted an application in accordance with Article 43(1) of Regulation (EU) No 528/2012 for authorisation of a biocidal product family named CMIT-MIT Aqueous 1.5-15 of product-types 2, 4, 6, 11, 12 and 13, as described in Annex V to that Regulation, providing written confirmation that the competent authority of France had agreed to evaluate the application. The application was recorded under case number BC-CY032700-28 in the Register for Biocidal Products. (2) CMIT-MIT Aqueous 1.5-15 contains a mixture of CMIT/MIT, as the active substance, which is included in the Union list of approved active substances referred to in Article 9(2) of Regulation (EU) No 528/2012. (3) On 31 March 2020, the evaluating competent authority submitted, in accordance with Article 44(1) of Regulation (EU) No 528/2012, the assessment report and the conclusions of its evaluation to the European Chemicals Agency (the Agency). (4) On 18 December 2020, the Agency submitted to the Commission an opinion ECHA opinion of 3 December 2020 on the Union authorisation of CMIT-MIT Aqueous 1.5-15 (ECHA/BPC/273/2020), https://echa.europa.eu/bpc-opinions-on-union-authorisation. , the draft summary of the biocidal product characteristics (SPC) of CMIT-MIT Aqueous 1.5-15 and the final assessment report on the biocidal product family in accordance with Article 44(3) of Regulation (EU) No 528/2012. (5) The opinion concludes that CMIT-MIT Aqueous 1.5-15 is a biocidal product family within the meaning of Article 3(1), point (s), of Regulation (EU) No 528/2012, that it is eligible for Union authorisation in accordance with Article 42(1) of that Regulation and that subject to compliance with the draft SPC, it meets the conditions laid down in Article 19(1) and (6) of that Regulation. (6) On 15 January 2021, the Agency transmitted to the Commission the draft SPC in all the official languages of the Union in accordance with Article 44(4) of Regulation (EU) No 528/2012. (7) The Commission concurs with the opinion of the Agency and considers it therefore appropriate to grant a Union authorisation for CMIT-MIT Aqueous 1.5-15. (8) The measures provided for in this Regulation are in accordance with the opinion of the Standing Committee on Biocidal Products, HAS ADOPTED THIS REGULATION:

Article 1

A Union authorisation with authorisation number EU-0025449-0000 is granted to Nutrition & Biosciences Netherlands B.V. for the making available on the market and use of the biocidal product family CMIT-MIT Aqueous 1.5-15 in accordance with the summary of the biocidal product characteristics set out in the Annex.

The Union authorisation is valid from 20 September 2022 until 31 August 2032.

Article 2

This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union. This Regulation shall be binding in its entirety and directly applicable in all Member States. Done at Brussels, 22 July 2022. For the Commission The President Ursula VON DER LEYEN

Annex

ANNEX Summary of product characteristics for a biocidal product family CMIT-MIT Aqueous 1.5-15 Product type 2 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants) Product type 4 - Food and feed area (Disinfectants) Product type 6 - Preservatives for products during storage (Preservatives) Product type 11 - Preservatives for liquid-cooling and processing systems (Preservatives) Product type 12 - Slimicides (Preservatives) Product type 13 - Working or cutting fluid preservatives (Preservatives) Authorisation number: EU-0025449-0000 R4BP asset number: EU-0025449-0000 PART I FIRST INFORMATION LEVEL

1. ADMINISTRATIVE INFORMATION 1.1. Family name NameCMIT-MIT Aqueous 1.5-15 1.2. Product type(s) Product type(s) PT02 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants) PT04 - Food and feed area (Disinfectants) PT06 - Preservatives for products during storage (Preservatives) PT11 - Preservatives for liquid-cooling and processing systems (Preservatives) PT12 - Slimicides (Preservatives) PT13 - Working or cutting fluid preservatives (Preservatives) 1.3. Authorisation holder Name and address of the authorisation holderNameMC (Netherlands) 1 B.V.AddressWillem Einthovenstraat 4, 2342BH Oegstgeest Netherlands Authorisation numberEU-0025449-0000R4BP asset numberEU-0025449-0000Date of the authorisation20 September 2022Expiry date of the authorisation31 August 2032 1.4. Manufacturer(s) of the biocidal products Name of manufacturerAD Productions BVAddress of manufacturerMarkweg Zuid 27, 4794 SN Heijningen, NetherlandsLocation of manufacturing sitesMarkweg Zuid 27, 4794 SN Heijningen, NetherlandsName of manufacturerJiangsu FOPIA Chemicals Co., LtdAddress of manufacturerTouzeng Village, 224555 Binhuai Town, Binhai County, Yancheng City, Jiangsu, ChinaLocation of manufacturing sitesTouzeng Village, 224555 Binhuai Town, Binhai County, Yancheng City, Jiangsu, ChinaName of manufacturerAcquaflex S.R.LAddress of manufacturerVigano di Gaggiano, 20083 Milan, ItalyLocation of manufacturing sitesVigano di Gaggiano, 20083 Milan, ItalyName of manufacturerLABORATORIOS MIRET, S.A.Address of manufacturerHercules, 18, 08228 Terrassa, Barcelona, SpainLocation of manufacturing sitesHercules, 18, 08228 Terrassa, Barcelona, SpainName of manufacturerHYDRACHIMAddress of manufacturerRoute de Saint Poix, 35370 LE PERTRE, FranceLocation of manufacturing sitesRoute de Saint Poix, 35370 LE PERTRE, FranceName of manufacturerDAXEL srl.Address of manufacturervia Pietro Nenni 8, 42048 Rubiera RE, ItalyLocation of manufacturing sitesvia Pietro Nenni 8, 42048 Rubiera RE, Italy

Name of manufacturerAquatreat Chemical Products LtdAddress of manufacturerUnit 7, Abbey Industrial Estate, 24 Willow Lane, CR4 4NA Mitcham, United KingdomLocation of manufacturing sitesUnit 7, Abbey Industrial Estate, 24 Willow Lane, CR4 4NA Mitcham, United KingdomName of manufacturerFlexfill s.r.o.Address of manufacturerSiřejovická 1213, 410 02 Lovosice, Czech RepublicLocation of manufacturing sitesSiřejovická 1213, 410 02 Lovosice, Czech RepublicName of manufacturerSopura SAAddress of manufacturer199 rue de trazegnies, 6180 Courcelles, BelgiumLocation of manufacturing sites199 rue de trazegnies, 6180 Courcelles, BelgiumName of manufacturerStenco IndustrialAddress of manufacturerC/ Gran Vial, 50817 Montornès del Vallès, Barcelona, SpainLocation of manufacturing sitesC/ Gran Vial, 50817 Montornès del Vallès, Barcelona, SpainName of manufacturerSUEZ WTS France S.A.S.Address of manufacturer44, Rue Paul Sabatier Z.I. Nord, 71530 Crissey, FranceLocation of manufacturing sites44, Rue Paul Sabatier Z.I. Nord, 71530 Crissey, FranceName of manufacturerQUIPROCALT S.L.Address of manufacturerCalle Lleida, 2 (Pol Ind Empalme), 43712 Llorenç del Penedès. Tarragona, SpainLocation of manufacturing sitesCalle Lleida, 2 (Pol Ind Empalme), 43712 Llorenç del Penedès. Tarragona, SpainName of manufacturernv Buckman LaboratoriesAddress of manufacturerWondelgemkaai 159, 9000 Gent, BelgiumLocation of manufacturing sitesWondelgemkaai 159, 9000 Gent, Belgium Name of manufacturerN.C.R. Biochemical S.p.A.Address of manufacturerVia dei Carpentieri n.8, 40050 Castello d’Argile, ItalyLocation of manufacturing sitesVia dei Carpentieri n.8, 40050 Castello d’Argile, ItalyName of manufacturerAlliance ProductionAddress of manufacturer4 BOULEVARD DEODAT DE SEVERAC, 31770 COLOMIERS, FranceLocation of manufacturing sites4 BOULEVARD DEODAT DE SEVERAC, 31770 COLOMIERS, FranceName of manufacturerURQUIMIA S.L.Address of manufacturerPOL. IND. DE ARASO C/ERREGEOIANA 2G, 20305 Irún, Guipúzcoa, SpainLocation of manufacturing sitesPOL. IND. DE ARASO C/ERREGEOIANA 2G, 20305 Irún, Guipúzcoa, SpainName of manufacturerKalon Mantenimiento Industrial S.A.Address of manufacturerAvenida de la Industria 4, 28823 Coslada, Madrid, SpainLocation of manufacturing sitesAvenida de la Industria 4, 28823 Coslada, Madrid, SpainName of manufacturerFiltrotech SarlAddress of manufacturerRoute des Jeunes 5D, 1227 Les Acacias / Genève, SwitzerlandLocation of manufacturing sitesRoute des Jeunes 5D, 1227 Les Acacias / Genève, SwitzerlandName of manufacturerHelamin France SarlAddress of manufacturerLe Technoparc, 135 rue Thomas-Edison, 01630 Saint Genis Pouilly, FranceLocation of manufacturing sitesLe Technoparc, 135 rue Thomas-Edison, 01630 Saint Genis Pouilly, FranceName of manufacturerOdyssée EnvironnementAddress of manufacturerZ.A de la Belle Croix, 72510 Requeil, FranceLocation of manufacturing sitesZ.A de la Belle Croix, 72510 Requeil, France Name of manufacturerMSGA SERVIVAPAddress of manufacturer50 Rue Jean Zay Bâtiment D1, 69800 ST PRIEST, FranceLocation of manufacturing sites50 Rue Jean Zay Bâtiment D1, 69800 ST PRIEST, FranceName of manufacturerTECNA ACONDICIONAMIENTOS DE AGUA S.AAddress of manufacturerLetxumborro Hiribidea, 52, 20305 Irun, Guipúzcoa, SpainLocation of manufacturing sitesLetxumborro Hiribidea, 52, 20305 Irun, Guipúzcoa, SpainName of manufacturerh2o facilities saAddress of manufacturerav. des Grandes-Communes 8, CH-1213 Petit-Lancy, FranceLocation of manufacturing sitesav. des Grandes-Communes 8, CH-1213 Petit-Lancy, FranceName of manufacturerFUPINAX S.L.Address of manufacturerPolígono Industrial El Saladar I, C/ Molina, Nave 4, 30564 Lorquí, SpainLocation of manufacturing sitesPolígono Industrial El Saladar I, C/ Molina, Nave 4, 30564 Lorquí, SpainName of manufacturerTresch/ chassieuAddress of manufacturer3 Rue Blaise Pascal, 69680 Chassieu, FranceLocation of manufacturing sites3 Rue Blaise Pascal, 69680 Chassieu, FranceName of manufacturerDUPUYAddress of manufacturer42 Rue Saint Martin, 08400 Quatre Champs, FranceLocation of manufacturing sites42 Rue Saint Martin, 08400 Quatre Champs, FranceName of manufacturerSUEZ Water Technologies and Solutions Belgium BVBAAddress of manufacturerToekomstlaan 54, Industriepark Wolfstee, 2200 HERENTALS, BelgiumLocation of manufacturing sitesToekomstlaan 54, Industriepark Wolfstee, 2200 HERENTALS, Belgium

Name of manufacturerBuckman Laboratories (Pty)LtdAddress of manufacturer1 Buckman Boulevard, 3700 Hammarsdale, South AfricaLocation of manufacturing sites1 Buckman Boulevard, 3700 Hammarsdale, South AfricaName of manufacturerEAUTEXAddress of manufacturer28 RUE KELLERMANN, 59100 ROUBAIX, FranceLocation of manufacturing sites28 RUE KELLERMANN, 59100 ROUBAIX, FranceName of manufacturerHydrogel-Chemie Wasseraufbereitungs-Gesellschaft mbHAddress of manufacturerZur Mersch 19, 59457 Werl, GermanyLocation of manufacturing sitesZur Mersch 19, 59457 Werl, GermanyName of manufacturersceoAddress of manufacturerZA PECHNAUQUIE SUD, 31340 VILLEMR SUR TARN, FranceLocation of manufacturing sitesZA PECHNAUQUIE SUD, 31340 VILLEMR SUR TARN, FranceName of manufacturerNutrition & Biosciences (Switzerland) GmbHAddress of manufacturerWolleraustrasse 15-17, CH-8807 Freienbach, SwitzerlandLocation of manufacturing sites Haven 1931 Geslecht, 9130 Kallo, Belgium Madoerastraat 10, 3199 KR Maasvlakte Rotterdam, Netherlands 1.5. Manufacturer(s) of the active substance(s) Active substanceMixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Name of manufacturerJiangsu FOPIA Chemicals Co., Ltd Address of manufacturerTouzeng Village, 224555 Binhuai Town, Binhai County, Yancheng City, Jiangsu, ChinaLocation of manufacturing sitesTouzeng Village, 224555 Binhuai Town, Binhai County, Yancheng City, Jiangsu, China 2. PRODUCT FAMILY COMPOSITION AND FORMULATION 2.1. Qualitative and quantitative information on the composition of the family Common nameIUPAC nameFunctionCAS numberEC numberContent (%)MinMaxMixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,220,9 2.2. Type(s) of formulation Formulation(s)AL - Any other liquid PART II SECOND INFORMATION LEVEL - META SPC(S) META SPC 1

1. META SPC 1 ADMINISTRATIVE INFORMATION 1.1. Meta SPC 1 identifier Identifiermeta-SPC 1 KATHON 13-15 Mg 1.2. Suffix to the authorisation number Number1-1 1.3. Product type(s) Product type(s) PT02 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants) PT04 - Food and feed area (Disinfectants) PT06 - Preservatives for products during storage (Preservatives) PT11 - Preservatives for liquid-cooling and processing systems (Preservatives) PT12 - Slimicides (Preservatives) PT13 - Working or cutting fluid preservatives (Preservatives)
2. META SPC 1 COMPOSITION 2.1. Qualitative and quantitative information on the composition of the meta SPC 1 Common nameIUPAC nameFunctionCAS numberEC numberContent (%)MinMaxMixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-918,820,9 2.2. Type(s) of formulation of the meta SPC 1 Formulation(s)AL - Any other liquid
3. HAZARD AND PRECAUTIONARY STATEMENTS OF THE META SPC 1

Hazard statements Harmful if swallowed. Harmful if inhaled. Toxic in contact with skin. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Very toxic to aquatic life with long lasting effects. Corrosive to the respiratory tract. May be corrosive to metals. Precautionary statements Do not breathe fume. Wash skin thoroughly after handling. Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Avoid release to the environment. Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. Rinse mouth. IF ON SKIN: Wash with plenty of water. Take off contaminated clothing. And wash it before reuse. IF SWALLOWED: Call a Poison Center or doctor if you feel unwell. If skin irritation or rash occurs: Get medical advice. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a Poison Center / doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Collect spillage. Store locked up. Keep only in original packaging. Absorb spillage to prevent material damage. Store in a corrosion-resistant container with a resistant inner liner. 4. AUTHORISED USE(S) OF THE META SPC 1 4.1. Use description Table 1 Use # 1 – Preservation of sump water in air conditioning and air washer systems Product typePT02 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including L. pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae Development stage: Field(s) of use Outdoor Preservation of sump water in air conditioning and air washer systems. Air conditioning systems and in air washer systems to preserve the sump water. Air washer systems are used extensively in textile factories and in the tobacco industry to scrub or clean the air and for fine control of temperature and humidity. Application method(s) Method: - Detailed description: Automatic and Manual Dosing The biocidal product is typically added in a central chilled water sump which supplies several air washers. The loading process may be conducted either manually or by automation. In the automated process, the biocide is metered directly into the sump from a holding tank or other type of bulk container by a dosimeter (pump). The feeding pipe must dose the biocidal product below the water level in order to limit its evaporation. Application rate(s) and frequency Application Rate: Curative application: Bacteria, yeasts and fungi. When the system is noticeably fouled, apply 5 to 14,9 mg C(M)IT/MIT (3:1) per Litre of water to be treated, as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Preventive application: algae When control is obtained, add a continuous or semi continuous feed of 3 to 5 mg C(M)IT/MIT (3:1) per L of water to be treated

Dilution (%): - Number and timing of application: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 5 to 14,9 mg C(M)IT/MIT (3:1) per Litre of water to be treated, as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Contact time of 1 hour. Preventive application: algae When control is obtained, add a continuous or semi continuous feed of 3 to 5 mg C(M)IT/MIT (3:1) per L of water to be treated. Regardless of the manner of treatment, the total concentration of the active ingredient C(M)IT/MIT (3:1) in the system should not exceed 14,9 mg/L in the sump water. Preliminary steps prior to addition: The biocidal product is automatically dosed to the system. Manual handling is necessary for the loading of the biocidal product into the dosing systems. Application Frequency: Nominally every 2 to 3 days or as needed to obtain control. Repeat until fouling is reduced to an acceptable level for controlling the microbial growth. Category(ies) of usersIndustrial Pack sizes and packaging material For industrial and professional users: High Density Poly Ethylene (HDPE) flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE Intermediate bulk container (IBC): 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.1.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). The CMIT/MIT biocidal products are used after a shock dose of free chlorine in this application as standard industry practice. 4.1.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of personal protective equipment (PPE) and application of technical and organisational risk mitigation measures (RMM): Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.1.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.1.4. Where specific to the use, the instructions for safe disposal of the product and its packaging

See general directions for use. 4.1.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.2. Use description Table 2 Use # 2 – Preservation of fluids in conveyor belts and pasteurisers Product typePT04 - Food and feed area (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of fluids in conveyor belts and pasteurisers The biocidal product is used for the preservation of process fluids in pasteurisers and conveyor belts used in food industry. The biocidal product is used in these systems to either control or kill bacteria and fungi. Application method(s) Method: Closed system Detailed description: Automated dosing The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing (e.g. collecting sump below the conveyor belt). Application rate(s) and frequency Application Rate: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 10 to 14,9 g C(M)IT/MIT (3:1) per m3 of water to be treated as post treatment after a shock dose of minimum 0,3 ppm of free chlorine Preventive application: Bacteria: When control is obtained, add a continuous or semi continuous feed of 2,5 to 5 g C(M)IT/MIT (3:1) per m3 of water to be treated. Dilution (%): - Number and timing of application: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 10 to 14,9 g C(M)IT/MIT (3:1) per m3 of water to be treated as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Contact time of 1 hour. Preventive application: Bacteria: When control is obtained, add a continuous or semi continuous feed of 2,5 to 5 g C(M)IT/MIT (3:1) per m3 of water to be treated. Preliminary steps prior to addition: The biocidal product is automatically dosed to system. Manual handling is necessary for the loading of containers containing the biocidal product into the dosing systems. Application Frequency: Nominally every 2 to 3 days or as needed to obtain control. Repeat until fouling is reduced to an acceptable level for controlling the microbial growth. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.2.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). The CMIT/MIT biocidal products are used after a shock dose of free chlorine in this application as standard industry practice. 4.2.2.

Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.2.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.2.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.2.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.3. Use description Table 3 Use # 3 – Long term offline preservation of reverse osmosis membranes used in potable water Product typePT04 - Food and feed area (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Long term offline preservation of reverse osmosis membranes used in potable water The C(M)IT/MIT (3:1) biocidal product is recommended for controlling biological growth in off-line trains reverse osmosis membranes producing potable water for extended periods of time. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. It is recommended that fouled membranes be cleaned prior to shut-down and preservation. Please refer to RO /NF supplier manual for membrane cleaning and system shutdown procedures. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. After complete filling of the trains RO/NF systems with the biocide solution, pumps are stopped (Off line treatment) for extended periods of time. Typically C(M)IT/MIT (3:1) solutions are prepared in the CIP (cleaning in place) tank and added via the dosing system. Dilution with the permeate water or high quality water is recommended for the preparation of the biocide solution.

Membranes should be soaked in the biocide solution during the shut-down period. Application rate(s) and frequency Application Rate: 7,5 -20 g of C(M)IT/MIT (3:1)/ m3 of water Dilution (%): - Number and timing of application: 7,5 -20 g of C(M)IT/MIT (3:1)/ m3 of water Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.3.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). Prior to taking the membranes back on-line, flush carefully the elements with permeate water in order to eliminate all the residual biocidal product. 4.3.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the whole system, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information) Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.3.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.3.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.3.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.4. Use description Table 4 Use # 4 – Preservation of paints and coatings Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Outdoor Preservation of paints and coatings (including electrodeposition) The biocidal product is recommended to control the growth of bacteria and yeasts in coatings applied by an electrodeposition process and associated rinse systems and in water-based paints and coatings in storage containers before use.

Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrial Pack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.4.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. 4.4.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (Mixing and Loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate.

The maximal concentration of products from Meta SPC 1, 2, 3 and 4 to be added in paints used must be below the threshold value of 15 ppm. 4.4.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.4.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.4.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.5. Use description Table 5 Use # 5 – Preservation of detergents and household products Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of detergents (washing and cleaning fluids) and household products. The biocidal product is recommended for the control of bacteria, yeast and fungi in detergents and cleaning fluids (i.e. hard surface cleaners (all-purpose cleaners), hand dish washing products, fabric softeners, laundry detergents), products used for car care, floor care, waxes, hard surface cleaners, pre-moistened sponges or mops, and the surfactants used in these types of products. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional and general public uses: 6-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacturing, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Institutional and Household products: (detergents, cleaners, softeners, etc.) Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional and general public uses: 6-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.5.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product.

Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. 4.5.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1 and 3 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal concentration of products from Meta SPC 1 and 3 to be added in detergents and household products used must be below the threshold value of 15 ppm. 4.5.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.5.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.5.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.6. Use description Table 6 Use # 6 – Preservation of fluids used in paper, textile and leather production - Curative treatment Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of fluids used in paper, textile and leather production - The biocidal product is used to reduce contamination by bacteria in textile additives (woven and non-woven, natural and synthetic including silicone emulsions) processing chemicals, all chemicals used in the leather process industry and paper additives (e.g. water pigment pastes, starch, natural gums, synthetic and natural latexes, sizing agents, coating binders, retention aids, dyes, fluorescent whitening agents, wet-strength resins) used in paper mills. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure.

Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Curative treatment: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Contact time: 24 hours For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.6.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.6.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of fluids used in paper, textile and leather production being above the threshold value of 15 ppm, exposure has to be limited by use of PPE protecting skin and mucous membranes potentially exposed and application of technical and organisational RMM:

Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. 4.6.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.6.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.6.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.7. Use description Table 7 Use # 7 – Preservation of glues and adhesives Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of glues and adhesives The biocidal product is recommended to control the growth of bacteria and yeasts in water-soluble and water-dispersed synthetic and natural adhesives and tackifiers in storage containers before use Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.7.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved.

It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm. 4.7.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of glues and adhesives being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.7.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.7.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.7.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.8. Use description Table 8 Use # 8 – Preservation of polymer lattices Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage:

Field(s) of use Indoor Preservation of polymer latexes The biocidal product is recommended for the control of bacteria, yeast and fungi in the manufacture, storage, and transport of latexes, synthetic polymers including Hydrolysed Poly Acryl Amide (HPAM) and biopolymers (e.g. xanthan, dextran.) natural latexes. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.8.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.8.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows:

protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of polymer lattices being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.8.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.8.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.8.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.9. Use description Table 9 Use # 9 – Preservation of biocides and fertilizers Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Outdoor Preservation of biocides and fertilizers The biocidal product is recommended to control the growth of bacteria and yeasts in fertilizers and biocidal products. Application method(s) Method: - Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room.

4.9.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.9.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1 and 3 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of biocides and fertilizers being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.9.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.9.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.9.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.10. Use description Table 10 Use # 10 – Preservation of mineral slurries Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of mineral slurries The biocidal product is recommended to control the growth of bacteria in aqueous-based inorganic/mineral slurries and inorganic pigments which are formulated into paints, coatings and paper. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.10.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.10.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information);

Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of mineral slurries being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.10.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.10.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.10.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.11. Use description Table 11 Use # 11 – Preservation of building products applied indoor only Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of building (construction) products (including sealants, caulks, plasters etc.) The biocidal product is recommended to control the growth of bacteria in building (construction) products (sealants, caulks, biopolymers, plasters, fillers, admixtures concrete additives, joints compounds,.). Application method(s) Method: - Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room.

4.11.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.11.2. Use-specific risk mitigation measures This use is restricted to the preservation of building material applied indoor only. During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of building products being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.11.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.11.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.11.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.12. Use description Table 12 Use # 12 – Preservation of electronic chemicals – Curative treatment Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of electronic chemicals The biocidal product is used to reduce contamination by bacteria, yeasts and fungi in electronic chemicals as Chemical Mechanical Polishing (CMP) silica slurries. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: Add at typical use rate between 10-30 mg C(M)IT/MIT (3:1) per L final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses Curative treatment: 10-30 mg C(M)IT/MIT (3:1) per kg final product to be treated. Contact time: 7 days For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.12.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.12.2. Use-specific risk mitigation measures During handling phases for products from Meta SPC 3 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice.

PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of electronic chemicals being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.12.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.12.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.12.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.13. Use description Table 13 Use # 13 – Preservation of inks Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of inks The biocidal product is recommended to control the growth of bacteria and yeasts in inks and ink components (printing inks lithographic, photographic, ink-jet fluids, water based dampening or fountain solutions inks used for textile printing). The biocidal product inhibits the growth of microorganisms, which would otherwise lead to odour formation, viscosity alteration, product discolouration and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product.

For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.13.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm. 4.13.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of inks being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.13.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use.

4.13.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.13.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.14. Use description Table 14 Use # 14 – Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) The biocidal product is recommended to control the growth of bacteria in functional fluids such as brake and hydraulic fluids, antifreeze additives, corrosion inhibitors, spinning fluids. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.14.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.14.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc…) being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.14.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.14.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.14.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.15. Use description Table 15 Use # 15 – Preservation of laboratory reagents Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of laboratory reagents . The biocidal product is recommended to control the growth of bacteria and yeasts in laboratory reagents. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated.

Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 1 L HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.15.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.15.2. Use-specific risk mitigation measures During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of laboratory reagents being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device;

Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.15.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.15.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.15.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.16. Use description Table 16 Use # 16 – Offline preservation of industrial reverse osmosis membranes Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Offline preservation of industrial reverse osmosis membranes The biocidal product is recommended to control the growth of bacteria of reverse osmosis and nanofiltration membranes producing industrial water for extended periods of time. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to ensure adequate mixing throughout the system. After complete filling of the trains RO/NF systems with the biocide solution, pumps are stopped (Off line treatment) for extended periods of time. Typically C(M)IT/MIT (3:1) solutions are prepared in the CIP (cleaning in place) tank and added via the dosing system. Dilution with permeate water or high quality water is recommended for the preparation of the biocide solution. Membranes should be soaked in the biocide solution during the shut-down period. Application rate(s) and frequency Application Rate: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1). Dilution (%): - Number and timing of application: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1). Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.16.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

4.16.2. Use-specific risk mitigation measures Rinse the system with water prior to perform the maintenance of the system. During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.16.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.16.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.16.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.17. Use description Table 17 Use # 17 – Preservation of liquids used in closed recirculating cooling systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in closed recirculating cooling systems (Closed re-circulating cooling water systems comprise compressor cooling, air conditioning chilled water, boilers, engine jacket cooling, power supply cooling, and other industrial processes). The biocidal product is used to control the growth of aerobes and anaerobes bacteria, yeast, fungi, and biofilm in the circulating water of closed systems Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative efficacy:- against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours - against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours.- against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours. Preventive efficacy:- against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. - against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water.

Dilution (%): - Number and timing of application: Curative efficacy: against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours Preventive efficacy: against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.17.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.17.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.17.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.17.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.17.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.18. Use description Table 18 Use # 18 – Preservation of liquids used in small open recirculating cooling systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae (green algae and cyanobacteria) Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in small open recirculating cooling systems (blowdown and recirculating flow rates, as well as total volume of water limited to 2 m3/h, and 100 m3/h and 300 m3 respectively) Process and cooling water: Used to control the growth of bacteria, algae, fungi and biofilm Application method(s) Method: Open system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative treatment Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water, - against biofilm (including L. pneumophila) at 1,5 to 14,9 g C(M)IT/MIT (3:1) / m3 of water, - against fungi (including yeast) at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: - against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, - against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. Preventive treatment: against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.18.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.18.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation;

Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Cooling fluid must not enter surface water directly. Use product only in premises that are connected to a STP. The product can only be used when the cooling towers are equipped with drift eliminators that reduce the drift at least by 99 %. 4.18.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.18.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.18.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.19. Use description Table 19 Use # 19 – Preservation of liquids used in pasteurizers, conveyor belts and air washers Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae (green algae and cyanobacteria) Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in non-food pasteurizers and conveyor belts, air washers. Application method(s) Method: - Detailed description: The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing (e.g. collecting sump below the conveyor belt). The feeding pipe is used to dose the biocidal product below the water level in order to limit its evaporation. Application rate(s) and frequency Application Rate: Curative treatment: -against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water

Contact time: 48 hours. Preventive treatment: Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.19.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. Air washers: For use only in industrial air-washer systems that maintain effective mist eliminating components. 4.19.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.19.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.19.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.19.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.20. Use description Table 20 Use # 20 – Preservation of wood treatment solutions Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Scientific name: fungi Common name: other Development stage: Field(s) of use Indoor Outdoor Preservation of wood treatment solutions for application on wood of classes 1, 2 and 3 only. The biocidal product is used as a preservative for aqueous wood preservative treatment solution during the wet-state process used in timber treatment solutions.

Application method(s) Method: - Detailed description: — Application rate(s) and frequency Application Rate: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution Dilution (%): - Number and timing of application: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.20.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. The biocidal product is not intended to function as a wood preservative against wood destroying fungus relative to product type 8. 4.20.2. Use-specific risk mitigation measures During handling phases (mixing and loading) and cleaning phases, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The product shall not be used in a wood treatment solution to be applied to wood which may come in direct contact with food, feeding stuff and livestock animals The product can be used to preserve wood treatment solutions for the treatment of wood in use classes 1, 2 and 3 only. The product can be used in a wood treatment solution where the industrial application processes of wood treatment can be carried out within a contained area situated on impermeable hard standing with bunding to prevent run-off and a recovery system in place (e.g. sump). The product can be used in wood treatment solutions for the preservation of freshly treated timber, which after treatment is stored under shelter or on impermeable hard standing, or both, to prevent direct losses to soil, sewer or water. Any losses of wood treatment solution shall be collected for reuse or disposal.

The product can be used only in wood treatment solutions for industrial application if these cannot be released to soil, ground- and surface water or any kind of sewer and the wood treatment solutions and/or the product are collected and reused or disposed of as hazardous waste. The biocidal product can be used only in wood treatment solutions used for the treatment of objects or materials which are stored until completely dried on impermeable ground and under roof, to avoid leakage into the soil. 4.20.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.20.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.20.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.21. Use description Table 21 Use # 21 – Preservation of recirculating fluids used in textile and fiber processing, leather processing, photo-processing and fountain solution systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of recirculating fluids used in textile, fiber processing, leather processing, photo-processing and fountain solution systems C(M)IT/MIT (3:1) biocidal products are used for the preservation of textile and spinning fluids, photo processing solutions, leather process (e.g. washing and soaking treatment stages) and printing fountain solutions to control the integrity of recirculating fluid by reducing microbial contamination in the bulk solution. Application method(s) Method: - Detailed description: Manual and automated dosing. The preservation of all end-products is performed in most cases highly automated by industrial users The biocidal product is added to the central sump, basin or recirculating lines in an area with adequate mixing. Application rate(s) and frequency Application Rate: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid Dilution (%): - Number and timing of application: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid Contact time 5 days Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.21.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product.

4.21.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Liquids used in textile and fiber processing fluids must not enter surface water directly. Use product only in premises that are connected to a STP. Recirculating liquids in photoprocessing systems and fountain solution systems must not enter surface water directly. Use product only in premises that are connected to a STP. 4.21.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.21.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.21.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.22. Use description Table 22 Use # 22 – Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems. The biocidal product is used for preservation of fluids in pre- treatment processes (Cleaning treatment for grease removal and soil, degreasing Phosphating process, Rinse off tanks) paint spray booths and electrodeposition coating systems (e.g. cataphoretic baths) applied in Car Refinishing and Original equipment Car Manufacturing to control the integrity of recirculating fluid by reducing microbial contamination from bacteria and fungi in the bulk solution. Application method(s) Method: - Detailed description: — Application rate(s) and frequency

Application Rate: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. Dilution (%): - Number and timing of application: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. The biocidal product is added at the time of manufacture, storage or shipment. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.22.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.22.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.22.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.22.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.22.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.23. Use description Table 23 Use # 23 – Preservation of liquids used in closed recirculating heating systems and associated pipework Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use— Target organism(s) (including development stage) Common name: Bacteria (anaerobes and aerobes (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage:

Common name: Fungi Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in closed recirculating heating systems and associated pipework. Pre-commission biocide flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. Closed recirculating heating systems: pre-commission biocidal product flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. The biocidal product is used to control the growth of aerobic and anaerobic bacteria, fungi and biofilm in the circulating water of closed systems. Closed systems are less susceptible to corrosion, scaling and biological fouling than open systems. However microbial problems can occur, if the system is left filled and untreated. This is due to the presence of nitrite and glycols used as nutrients by microbes. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing. The feeding pipe must dose the biocidal product below the water level in order to limit the evaporation of the biocidal product. Application rate(s) and frequency Application Rate: Curative treatment - against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) - against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Preventive treatment - against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water - against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) Contact time: 24 hours against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Contact time: 48 hours Preventive treatment against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water and against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.23.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.23.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.23.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.23.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.23.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.24. Use description Table 24 Use # 24 – Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.) Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Outdoor Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.) Application method(s) Method: - Detailed description: — Application rate(s) and frequency Application Rate: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution. Dilution (%): - Number and timing of application: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L

All products should be transport and stored in a vented room. 4.24.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.24.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.24.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.24.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.24.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.25. Use description Table 25 Use # 25 – Slimicide treatment in the de-inking process of the pulp and paper Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Slimicide treatment in the de-inking process of the pulp and paper. Recycling paper /deinking paper mills. Deinking process is a manufacturing paper process of removing printing inks from waste paper-fibers to produce deinked pulp. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product is automatically dosed by pump and fixed pipes into the circuit, usually in the pulper below the water level. Application rate(s) and frequency Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated.

Dilution (%): - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.25.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.25.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.25.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.25.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.25.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.26. Use description Table 26 Use # 26 – Slimicide treatment in the wet-end stage of paper manufacturing process Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Slimicide treatment in the wet-end stage of the paper manufacturing process (paper mills, wet-end stage (water circuits), and paper mills process system).

Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Dilution (%): - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.26.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.26.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The use of C(M)IT/MIT (3:1) containing products for the slimicide treatment in the wet-end stage of the paper manufacturing process is restricted to (a) curative treatments in plants connected to a slimicide-free water from a pulp mill and only for the treatment of the short circulation of the paper mill; and (b) preventive treatments, and, for both cases, only if the factory’s waste water is purified in an on-site (full) industrial sewage treatment plant with a minimal capacity of 5000 m3 per day as described in the Industrial Emission Directive 2010/75/EU (Best Available Techniques for the production of pulp, paper and board) and if a dilution of at least 200 times in surface water is achieved after the industrial sewage treatment plant.

4.26.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.26.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.26.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.27. Use description Table 27 Use # 27 – Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF membranes Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF membranes Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Biocidal product application on a routine basis will prevent biofilm growth on Reverse Osmosis or Nano Filtration membrane surfaces, feed spacer, filter media and pipework. The biocidal product should be dispensed to the feed water at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid Dilution (%): - Number and timing of application: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.27.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.27.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information);

protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Use product only in premises that are connected to a STP. 4.27.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.27.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.27.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.28. Use description Table 28 Use # 28 – Products to control microbial deterioration in fluids used for working or cutting metal, glass or other materials Product typePT13 - Working or cutting fluid preservatives (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Products to control microbial deterioration in fluids used for working or cutting metal, glass or other materials The biocidal product is recommended to control the growth of bacteria and fungi in fluids used for metalworking fluids (cutting, grinding, rolling, drawing, etc.) metal surface treatment (aqueous multipurpose and de-watering rust cleaner fluids, etc.) and cutting fluids for glass or other materials. Application method(s) Method: - Detailed description: The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Curative treatment: When the system is noticeably fouled, apply 14,9 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Preventive treatment: When control is obtained, adding 10 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Dilution (%): - Number and timing of application: Curative treatment: When the system is noticeably fouled, apply 14,9 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Contact time: 24 h Preventive treatment: When control is obtained, adding 10 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.28.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product.

4.28.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.28.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.28.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.28.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 5. GENERAL DIRECTIONS FOR USE Instructions for use, risk mitigation measures and other directions for use under this section are valid for any authorised uses within the meta SPC 1. OF THE META SPC 1 5.1. Instructions for use The duration of the effect is dependent on the performance requirements of the customer for their preserved material and on the specific ingredients composition and pH of the preserved product. Always read the label or leaflet before use and follow all the instructions provided. Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.) PRECAUTIONARY MEASURES DURING STORAGE AND TRANSPORT: Keep in a well-ventilated place. The product as supplied may evolve gas (largely carbon dioxide) slowly. To prevent the buildup of pressure the product is packaged in specially vented containers, where necessary. Keep this product in the original container when not in use. Container must be stored and transported in an upright position to prevent spilling the contents through the vent, where fitted. 5.2. Risk mitigation measures — 5.3. Particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment Skin contact: Remove contaminated clothing and shoes. Wash contaminated skin with water. Contact poison treatment specialist if symptoms occur. Eye contact: Immediately flush with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses if easy to do. Continue to rinse with tepid water for at least 30 minutes. Call 112/ambulance for medical assistance.

Ingestion: Wash out mouth with water. Contact poison treatment specialist. Seek medical advice immediately if symptoms occur and/or large quantities have been ingested. Do not give fluids or induce vomiting. Inhalation (of spray mist): Remove victim to fresh air and keep at rest in a position comfortable for breathing. Seek medical advice immediately if symptoms occur and/or large quantities have been inhaled. In case of impaired consciousness place in recovery position and seek medical advice immediately. Keep the container or label available. 5.4. Instructions for safe disposal of the product and its packaging Do not discharge unused product on the ground, into water courses, into pipes (e.g. sink, toilets) nor down the drains. Dispose of unused product, its packaging and all other waste, in accordance with local regulations. 5.5. Conditions of storage and shelf-life of the product under normal conditions of storage Conditions for safe storage, including any incompatibilities: Keep in a dry, cool and well-ventilated place, in the original container. Protect from frost Shelf-life: 24 months Protect from sunlight. Recommendation: If a metal packaging is used, a varnish layer should be applied. 6. OTHER INFORMATION — 7. THIRD INFORMATION LEVEL: INDIVIDUAL PRODUCTS IN THE META SPC 1 7.1. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ WT BIOCIDEMarket area: EUKATHON™ WTMarket area: EU KATHON™LX BIOCIDEMarket area: EUKATHON™ LXMarket area: EUKATHON™ LX MicrobicideMarket area: EUKATHON™886MW BIOCIDEMarket area: EUKATHON™ 886 F BIOCIDEMarket area: EUBansan 160Market area: EUBiocide KT1400WTMarket area: EUBiocide KT1400LXMarket area: EUBiocide KT1400MWMarket area: EUKT1400MWMarket area: EUKT1400WTMarket area: EUHydrex™ 7320Market area: EUMIRECIDE-KW/650Market area: EUobbio211Market area: EUAQUACIDE C 140Market area: EUAQUACIDE C 15Market area: EUAQUACIDE C 21Market area: EUAQUACIDE C 30Market area: EUBAC 416Market area: EUBIOSTOP 140Market area: EUBIOSTOP 15Market area: EUBIOSTOP 21Market area: EUBIOSTOP 30Market area: EUCAT 3693Market area: EUGWC 3363Market area: EUGWC 3630Market area: EUGWE 3693Market area: EUIWC BACTERICIDE 416Market area: EUIsocil® 14Market area: EUFrance Algue 232Market area: EU KT1400LXMarket area: EUAuthorisation numberEU-0025449-0001 1-1Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-920,3 7.2. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ CF 1400 BIOCIDEMarket area: EUBiocide KT1400Market area: EUKT1400Market area: EUhygel KW 60 B ATESTEOMarket area: EUIsocil® Ultra 14Market area: EUMK3201Market area: EUFINEAMINMarket area: EUAuthorisation numberEU-0025449-0002 1-1Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-920,5

META SPC 2

1. META SPC 2 ADMINISTRATIVE INFORMATION 1.1. Meta SPC 2 identifier Identifiermeta-SPC 2 KATHON 13-15 Na 1.2. Suffix to the authorisation number Number1-2 1.3. Product type(s) Product type(s)PT06 - Preservatives for products during storage (Preservatives)
2. META SPC 2 COMPOSITION 2.1. Qualitative and quantitative information on the composition of the meta SPC 2 Common nameIUPAC nameFunctionCAS numberEC numberContent (%)MinMaxMixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-918,820,9 2.2. Type(s) of formulation of the meta SPC 2 Formulation(s)AL - Any other liquid
3. HAZARD AND PRECAUTIONARY STATEMENTS OF THE META SPC 2 Hazard statements May be corrosive to metals. Harmful if swallowed. Harmful if inhaled. Toxic in contact with skin. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Very toxic to aquatic life with long lasting effects. Corrosive to the respiratory tract. Precautionary statements Do not breathe fume. Wash skin thoroughly after handling. Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Avoid release to the environment. Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. Rinse mouth. IF ON SKIN: Wash with plenty of water. Take off contaminated clothing. And wash it before reuse. IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. If skin irritation or rash occurs: Get medical advice. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Collect spillage. Store locked up. Keep only in original packaging. Absorb spillage to prevent material damage. Store in a corrosion-resistant container with a resistant inner liner.
4. AUTHORISED USE(S) OF THE META SPC 2 4.1. Use description Table 29 Use # 1 – Preservation of paints and coatings Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Outdoor Preservation of paints and coatings (including electrodeposition) The biocidal product is recommended to control the growth of bacteria and yeasts in coatings applied by an electrodeposition process and associated rinse systems and in water-based paints and coatings in storage containers before use. Application method(s) Method: Closed system Detailed description:

Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.1.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. 4.1.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (Mixing and Loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal concentration of products from Meta SPC 1, 2, 3 and 4 to be added in paints used must be below the threshold value of 15 ppm.

4.1.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.1.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.1.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.2. Use description Table 30 Use # 2 – Preservation of fluids used in paper, textile and leather production - Curative treatment Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of fluids used in paper, textile and leather production - The biocidal product is used to reduce contamination by bacteria in textile additives (woven and non-woven, natural and synthetic including silicone emulsions) processing chemicals, all chemicals used in the leather process industry and paper additives (e.g. water pigment pastes, starch, natural gums, synthetic and natural latexes, sizing agents, coating binders, retention aids, dyes, fluorescent whitening agents, wet-strength resins) used in paper mills. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Curative treatment: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Contact time: 24 hours For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.2.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved.

It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.2.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of fluids used in paper, textile and leather production being above the threshold value of 15 ppm, exposure has to be limited by use of PPE protecting skin and mucous membranes potentially exposed and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. 4.2.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.2.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.2.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.3. Use description Table 31 Use # 3 – Preservation of glues and adhesives Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of glues and adhesives The biocidal product is recommended to control the growth of bacteria and yeasts in water-soluble and water-dispersed synthetic and natural adhesives and tackifiers in storage containers before use

Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.3.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm. 4.3.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information);

protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of glues and adhesives being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.3.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.3.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.3.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.4. Use description Table 32 Use # 4 – Preservation of polymer lattices Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of polymer latexes The biocidal product is recommended for the control of bacteria, yeast and fungi in the manufacture, storage, and transport of latexes, synthetic polymers including Hydrolysed Poly Acryl Amide (HPAM) and biopolymers (e.g. xanthan, dextran.) natural latexes. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material

For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.4.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.4.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of polymer lattices being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.4.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.4.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.4.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use.

4.5. Use description Table 33 Use # 5 – Preservation of mineral slurries Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of mineral slurries The biocidal product is recommended to control the growth of bacteria in aqueous-based inorganic/mineral slurries and inorganic pigments which are formulated into paints, coatings and paper. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.5.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.5.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects;

Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of mineral slurries being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.5.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.5.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.5.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.6. Use description Table 34 Use # 6 – Preservation of building products applied indoor only Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of building (construction) products (including sealants, caulks, plasters etc.) The biocidal product is recommended to control the growth of bacteria in building (construction) products (sealants, caulks, biopolymers, plasters, fillers, admixtures concrete additives, joints compounds,.). Application method(s) Method: - Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated.

For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.6.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.6.2. Use-specific risk mitigation measures This use is restricted to the preservation of building material applied indoor only. During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of building products being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.6.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.6.4. Where specific to the use, the instructions for safe disposal of the product and its packaging

See general directions for use. 4.6.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.7. Use description Table 35 Use # 7 – Preservation of inks Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of inks The biocidal product is recommended to control the growth of bacteria and yeasts in inks and ink components (printing inks lithographic, photographic, ink-jet fluids, water based dampening or fountain solutions inks used for textile printing). The biocidal product inhibits the growth of microorganisms, which would otherwise lead to odour formation, viscosity alteration, product discolouration and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users:- HDPE flask: 5 L (nominal)- HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)- Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L- HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.7.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm.

4.7.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of inks being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.7.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.7.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.7.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.8. Use description Table 36 Use # 8 – Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) The biocidal product is recommended to control the growth of bacteria in functional fluids such as brake and hydraulic fluids, antifreeze additives, corrosion inhibitors, spinning fluids. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition.

Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.8.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.8.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc…) being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM:

Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.8.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.8.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.8.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 5. GENERAL DIRECTIONS FOR USE Instructions for use, risk mitigation measures and other directions for use under this section are valid for any authorised uses within the meta SPC 2. OF THE META SPC 2 5.1. Instructions for use The duration of the effect is dependent on the performance requirements of the customer for their preserved material and on the specific ingredients composition and pH of the preserved product. Always read the label or leaflet before use and follow all the instructions provided. Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.) PRECAUTIONARY MEASURES DURING STORAGE AND TRANSPORT: Keep in a well-ventilated place. The product as supplied may evolve gas (largely carbon dioxide) slowly. To prevent the buildup of pressure the product is packaged in specially vented containers, where necessary. Keep this product in the original container when not in use. Container must be stored and transported in an upright position to prevent spilling the contents through the vent, where fitted. 5.2. Risk mitigation measures — 5.3. Particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment Skin contact: Remove contaminated clothing and shoes. Wash contaminated skin with water. Contact poison treatment specialist if symptoms occur. Eye contact: Immediately flush with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses if easy to do. Continue to rinse with tepid water for at least 30 minutes. Call 112/ambulance for medical assistance. Ingestion: Wash out mouth with water. Contact poison treatment specialist. Seek medical advice immediately if symptoms occur and/or large quantities have been ingested. Do not give fluids or induce vomiting. Inhalation (of spray mist): Remove victim to fresh air and keep at rest in a position comfortable for breathing. Seek medical advice immediately if symptoms occur and/or large quantities have been inhaled. In case of impaired consciousness place in recovery position and seek medical advice immediately. Keep the container or label available. 5.4. Instructions for safe disposal of the product and its packaging Do not discharge unused product on the ground, into water courses, into pipes (e.g. sink, toilets) nor down the drains.

Dispose of unused product, its packaging and all other waste, in accordance with local regulations. 5.5. Conditions of storage and shelf-life of the product under normal conditions of storage Conditions for safe storage, including any incompatibilities: Keep in a dry, cool and well-ventilated place, in the original container. Protect from frost Shelf-life: 6 months Protect from sunlight. Recommendation: If a metal packaging is used, a varnish layer should be applied. 6. OTHER INFORMATION — 7. THIRD INFORMATION LEVEL: INDIVIDUAL PRODUCTS IN THE META SPC 2 7.1. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ LX 1400 BiocideMarket area: EUKATHON™ LX 1400Market area: EUAQUACIDE C 15 PMarket area: EUAQUACIDE C 21 PMarket area: EUAQUACIDE C 30 PMarket area: EUAQUACIDE C 140 PMarket area: EUBAC 416 PMarket area: EUBIOSTOP 140 PMarket area: EUBIOSTOP 15 PMarket area: EUBIOSTOP 21 PMarket area: EUBIOSTOP 30 PMarket area: EUCAT 3693 PMarket area: EUGWC 3363 PMarket area: EUGWC 3630 PMarket area: EUGWE 3693 PMarket area: EUIWC BACTERICIDE 416 PMarket area: EU Authorisation numberEU-0025449-0003 1-2Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-920,5 META SPC 3

1. META SPC 3 ADMINISTRATIVE INFORMATION 1.1. Meta SPC 3 identifier Identifiermeta-SPC 3 KATHON 1.5-4.5 Mg 1.2. Suffix to the authorisation number Number1-3 1.3. Product type(s) Product type(s) PT02 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants) PT04 - Food and feed area (Disinfectants) PT06 - Preservatives for products during storage (Preservatives) PT11 - Preservatives for liquid-cooling and processing systems (Preservatives) PT12 - Slimicides (Preservatives) PT13 - Working or cutting fluid preservatives (Preservatives)
2. META SPC 3 COMPOSITION 2.1. Qualitative and quantitative information on the composition of the meta SPC 3 Common nameIUPAC nameFunctionCAS numberEC numberContent (%)MinMaxMixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,26,5 2.2. Type(s) of formulation of the meta SPC 3 Formulation(s)AL - Any other liquid
3. HAZARD AND PRECAUTIONARY STATEMENTS OF THE META SPC 3 Hazard statements Harmful if inhaled. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Very toxic to aquatic life with long lasting effects. Corrosive to the respiratory tract. May be corrosive to metals. Harmful if swallowed. Precautionary statements Do not breathe fume. Wash skin thoroughly after handling. Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Avoid release to the environment. Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.

Take off contaminated clothing. And wash it before reuse. If skin irritation or rash occurs: Get medical advice. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Collect spillage. Store locked up. Keep only in original packaging. IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Store in a corrosion-resistant container with a resistant inner liner. Absorb spillage to prevent material damage. 4. AUTHORISED USE(S) OF THE META SPC 3 4.1. Use description Table 37 Use # 1 – Preservation of sump water in air conditioning and air washer systems Product typePT02 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae Development stage: Field(s) of use Outdoor Preservation of sump water in air conditioning and air washer systems. Air conditioning systems and in air washer systems to preserve the sump water. Air washer systems are used extensively in textile factories and in the tobacco industry to scrub or clean the air and for fine control of temperature and humidity. Application method(s) Method: Open and closed Systems Detailed description: Automatic and Manual Dosing The biocidal product is typically added in a central chilled water sump which supplies several air washers. The loading process may be conducted either manually or by automation. In the automated process, the biocide is metered directly into the sump from a holding tank or other type of bulk container by a dosimeter (pump). The feeding pipe must dose the biocidal product below the water level in order to limit its evaporation. Application rate(s) and frequency Application Rate: Curative application: Bacteria, yeasts and fungi. When the system is noticeably fouled, apply 5 to 14,9 mg C(M)IT/MIT (3:1) per Litre of water to be treated, as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Preventive application: algae When control is obtained, add a continuous or semi continuous feed of 3 to 5 mg C(M)IT/MIT (3:1) per L of water to be treated Dilution (%): - Number and timing of application: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 5 to 14,9 mg C(M)IT/MIT (3:1) per Litre of water to be treated, as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Contact time of 1 hour. Preventive application: algae When control is obtained, add a continuous or semi continuous feed of 3 to 5 mg C(M)IT/MIT (3:1) per L of water to be treated.

Regardless of the manner of treatment, the total concentration of the active ingredient C(M)IT/MIT (3:1) in the system should not exceed 14,9 mg/L in the sump water. Preliminary steps prior to addition: The biocidal product is automatically dosed to the system. Manual handling is necessary for the loading of the biocidal product into the dosing systems. Application Frequency: Nominally every 2 to 3 days or as needed to obtain control. Repeat until fouling is reduced to an acceptable level for controlling the microbial growth. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.1.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). The CMIT/MIT biocidal products are used after a shock dose of free chlorine in this application as standard industry practice. 4.1.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.1.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.1.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.1.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.2. Use description Table 38 Use # 2 – Preservation of fluids in conveyor belts and pasteurisers Product typePT04 - Food and feed area (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts

Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of fluids in conveyor belts and pasteurisers The biocidal product is used for the preservation of process fluids in pasteurisers and conveyor belts used in food industry. The biocidal product is used in these systems to either control or kill bacteria and fungi. Application method(s) Method: Closed system Detailed description: Automated dosing The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing (e.g. collecting sump below the conveyor belt). Application rate(s) and frequency Application Rate: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 10 to 14,9 g C(M)IT/MIT (3:1) per m3 of water to be treated as post treatment after a shock dose of minimum 0,3 ppm of free chlorine Preventive application: Bacteria: When control is obtained, add a continuous or semi continuous feed of 2,5 to 5 g C(M)IT/MIT (3:1) per m3 of water to be treated. Dilution (%): - Number and timing of application: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 10 to 14,9 g C(M)IT/MIT (3:1) per m3 of water to be treated as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Contact time of 1 hour. Preventive application: Bacteria: When control is obtained, add a continuous or semi continuous feed of 2,5 to 5 g C(M)IT/MIT (3:1) per m3 of water to be treated. Preliminary steps prior to addition: The biocidal product is automatically dosed to system. Manual handling is necessary for the loading of containers containing the biocidal product into the dosing systems. Application Frequency: Nominally every 2 to 3 days or as needed to obtain control. Repeat until fouling is reduced to an acceptable level for controlling the microbial growth. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.2.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). The CMIT/MIT biocidal products are used after a shock dose of free chlorine in this application as standard industry practice. 4.2.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects;

Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.2.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.2.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.2.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.3. Use description Table 39 Use # 3 – Long term offline preservation of reverse osmosis membranes used in potable water Product typePT04 - Food and feed area (Disinfectants)Where relevant, an exact description of the authorised use— Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Long term offline preservation of reverse osmosis membranes used in potable water The C(M)IT/MIT (3:1) biocidal product is recommended for controlling biological growth in off-line trains reverse osmosis membranes producing potable water for extended periods of time. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. It is recommended that fouled membranes be cleaned prior to shut-down and preservation. Please refer to RO /NF supplier manual for membrane cleaning and system shutdown procedures. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. After complete filling of the trains RO/NF systems with the biocide solution, pumps are stopped (Off line treatment) for extended periods of time. Typically C(M)IT/MIT (3:1) solutions are prepared in the CIP (cleaning in place) tank and added via the dosing system. Dilution with the permeate water or high quality water is recommended for the preparation of the biocide solution. Membranes should be soaked in the biocide solution during the shut-down period. Application rate(s) and frequency Application Rate: 7,5 -20 g of C(M)IT/MIT (3:1)/ m3 of water Dilution (%): - Number and timing of application: 7,5 -20 g of C(M)IT/MIT (3:1)/ m3 of water Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L

HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.3.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). Prior to taking the membranes back on-line, flush carefully the elements with permeate water in order to eliminate all the residual biocidal product. 4.3.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the whole system, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.3.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.3.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.3.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.4. Use description Table 40 Use # 4 – Preservation of paints and coatings Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Outdoor Preservation of paints and coatings (including electrodeposition) The biocidal product is recommended to control the growth of bacteria and yeasts in coatings applied by an electrodeposition process and associated rinse systems and in water-based paints and coatings in storage containers before use. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product.

Dilution (%): - Number and timing of application: The biocidal product is added at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.4.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. 4.4.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (Mixing and Loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal concentration of products from Meta SPC 1, 2, 3 and 4 to be added in paints used must be below the threshold value of 15 ppm. 4.4.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.4.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.4.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage

See general directions for use. 4.5. Use description Table 41 Use # 5 – Preservation of detergents and household products Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use— Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of detergents (washing and cleaning fluids) and household products. The biocidal product is recommended for the control of bacteria, yeast and fungi in detergents and cleaning fluids (i.e. hard surface cleaners (all-purpose cleaners), hand dish washing products, fabric softeners, laundry detergents), products used for car care, floor care, waxes, hard surface cleaners, pre-moistened sponges or mops, and the surfactants used in these types of products. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional and general public uses: 6-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacturing, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Institutional and Household products: (detergents, cleaners, softeners, etc.) Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional and general public uses: 6-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrial Pack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.5.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. 4.5.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1 and 3 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal concentration of products from Meta SPC 1 and 3 to be added in detergents and household products used must be below the threshold value of 15 ppm. 4.5.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.5.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.5.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.6. Use description Table 42 Use # 6 – Preservation of fluids used in paper, textile and leather production - Curative treatment Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of fluids used in paper, textile and leather production - The biocidal product is used to reduce contamination by bacteria in textile additives (woven and non-woven, natural and synthetic including silicone emulsions) processing chemicals, all chemicals used in the leather process industry and paper additives (e.g. water pigment pastes, starch, natural gums, synthetic and natural latexes, sizing agents, coating binders, retention aids, dyes, fluorescent whitening agents, wet-strength resins) used in paper mills. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition.

Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Curative treatment: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Contact time: 24 hours For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.6.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.6.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of fluids used in paper, textile and leather production being above the threshold value of 15 ppm, exposure has to be limited by use of PPE protecting skin and mucous membranes potentially exposed and application of technical and organisational RMM:

Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. 4.6.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.6.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.6.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.7. Use description Table 43 Use # 7 – Preservation of glues and adhesives Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of glues and adhesives The biocidal product is recommended to control the growth of bacteria and yeasts in water-soluble and water-dispersed synthetic and natural adhesives and tackifiers in storage containers before use Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.7.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved.

It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm. 4.7.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of glues and adhesives being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.7.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.7.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.7.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.8. Use description Table 44 Use # 8 – Preservation of polymer lattices Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage:

Field(s) of use Indoor Preservation of polymer latexes The biocidal product is recommended for the control of bacteria, yeast and fungi in the manufacture, storage, and transport of latexes, synthetic polymers including Hydrolysed Poly Acryl Amide (HPAM) and biopolymers (e.g. xanthan, dextran.) natural latexes. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.8.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.8.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows:

protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of polymer lattices being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.8.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.8.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.8.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.9. Use description Table 45 Use # 9 – Preservation of biocides and fertilizers Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Outdoor Preservation of biocides and fertilizers The biocidal product is recommended to control the growth of bacteria and yeasts in fertilizers and biocidal products. Application method(s) Method: - Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room.

4.9.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.9.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1 and 3 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of biocides and fertilizers being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.9.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.9.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.9.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.10. Use description Table 46 Use # 10 – Preservation of mineral slurries Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of mineral slurries The biocidal product is recommended to control the growth of bacteria in aqueous-based inorganic/mineral slurries and inorganic pigments which are formulated into paints, coatings and paper. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.10.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.10.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information);

Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of mineral slurries being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.10.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.10.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.10.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.11. Use description Table 47 Use # 11 – Preservation of building products applied indoor only Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of building (construction) products (including sealants, caulks, plasters etc.) The biocidal product is recommended to control the growth of bacteria in building (construction) products (sealants, caulks, biopolymers, plasters, fillers, admixtures concrete additives, joints compounds,.). Application method(s) Method: - Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room.

4.11.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.11.2. Use-specific risk mitigation measures This use is restricted to the preservation of building material applied indoor only. During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of building products being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.11.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.11.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.11.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.12. Use description Table 48 Use # 12 – Preservation of electronic chemicals – Curative treatment Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of electronic chemicals The biocidal product is used to reduce contamination by bacteria, yeasts and fungi in electronic chemicals as Chemical Mechanical Polishing (CMP) silica slurries. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: Add at typical use rate between 10-30 mg C(M)IT/MIT (3:1) per L final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses Curative treatment: 10-30 mg C(M)IT/MIT (3:1) per kg final product to be treated. Contact time: 7 days For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.12.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.12.2. Use-specific risk mitigation measures During handling phases for products from Meta SPC 3 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice.

PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of electronic chemicals being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.12.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.12.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.12.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.13. Use description Table 49 Use # 13 – Preservation of inks Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of inks The biocidal product is recommended to control the growth of bacteria and yeasts in inks and ink components (printing inks lithographic, photographic, ink-jet fluids, water based dampening or fountain solutions inks used for textile printing). The biocidal product inhibits the growth of microorganisms, which would otherwise lead to odour formation, viscosity alteration, product discolouration and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product.

For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users:- HDPE flask: 5 L (nominal)- HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)- Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L- HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.13.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm. 4.13.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of inks being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.13.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use.

4.13.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.13.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.14. Use description Table 50 Use # 14 – Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) The biocidal product is recommended to control the growth of bacteria in functional fluids such as brake and hydraulic fluids, antifreeze additives, corrosion inhibitors, spinning fluids. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.14.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.14.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc…) being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.14.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.14.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.14.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.15. Use description Table 51 Use # 15 – Preservation of laboratory reagents Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of laboratory reagents . The biocidal product is recommended to control the growth of bacteria and yeasts in laboratory reagents. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated.

Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 1 L HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.15.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.15.2. Use-specific risk mitigation measures During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of laboratory reagents being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device;

Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.15.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.15.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.15.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.16. Use description Table 52 Use # 16 – Offline preservation of industrial reverse osmosis membranes Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Offline preservation of industrial reverse osmosis membranes The biocidal product is recommended to control the growth of bacteria of reverse osmosis and nanofiltration membranes producing industrial water for extended periods of time. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to ensure adequate mixing throughout the system. After complete filling of the trains RO/NF systems with the biocide solution, pumps are stopped (Off line treatment) for extended periods of time. Typically C(M)IT/MIT (3:1) solutions are prepared in the CIP (cleaning in place) tank and added via the dosing system. Dilution with permeate water or high quality water is recommended for the preparation of the biocide solution. Membranes should be soaked in the biocide solution during the shut-down period. Application rate(s) and frequency Application Rate: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1). Dilution (%): - Number and timing of application: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1). Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.16.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

4.16.2. Use-specific risk mitigation measures Rinse the system with water prior to perform the maintenance of the system. During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.16.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.16.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.16.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.17. Use description Table 53 Use # 17 – Preservation of liquids used in closed recirculating cooling systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in closed recirculating cooling systems (Closed re-circulating cooling water systems comprise compressor cooling, air conditioning chilled water, boilers, engine jacket cooling, power supply cooling, and other industrial processes). The biocidal product is used to control the growth of aerobes and anaerobes bacteria, yeast, fungi, and biofilm in the circulating water of closed systems Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative efficacy:- against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours - against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours.- against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours. Preventive efficacy:- against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. - against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water.

Dilution (%): - Number and timing of application: Curative efficacy: against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours Preventive efficacy: against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.17.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.17.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.17.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.17.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.17.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.18. Use description Table 54 Use # 18 – Preservation of liquids used in small open recirculating cooling systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae (green algae and cyanobacteria) Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in small open recirculating cooling systems (blowdown and recirculating flow rates, as well as total volume of water limited to 2 m3/h, and 100 m3/h and 300 m3 respectively) Process and cooling water: Used to control the growth of bacteria, algae, fungi and biofilm Application method(s) Method: Open system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative treatment Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water, - against biofilm (including L. pneumophila) at 1,5 to 14,9 g C(M)IT/MIT (3:1) / m3 of water, - against fungi (including yeast) at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: - against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, - against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. Preventive treatment: against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.18.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.18.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation;

Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Cooling fluid must not enter surface water directly. Use product only in premises that are connected to a STP. The product can only be used when the cooling towers are equipped with drift eliminators that reduce the drift at least by 99 %. 4.18.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.18.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.18.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.19. Use description Table 55 Use # 19 – Preservation of liquids used in pasteurizers, conveyor belts and air washers Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae (green algae and cyanobacteria) Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in non-food pasteurizers and conveyor belts, air washers. Application method(s) Method: - Detailed description: The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing (e.g. collecting sump below the conveyor belt). The feeding pipe is used to dose the biocidal product below the water level in order to limit its evaporation. Application rate(s) and frequency Application Rate: Curative treatment: -against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water

Contact time: 48 hours. Preventive treatment: Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.19.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. Air washers: For use only in industrial air-washer systems that maintain effective mist eliminating components. 4.19.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.19.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.19.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.19.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.20. Use description Table 56 Use # 20 – Preservation of wood treatment solutions Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Scientific name: fungi Common name: other Development stage: Field(s) of use Indoor Outdoor Preservation of wood treatment solutions for application on wood of classes 1, 2 and 3 only. The biocidal product is used as a preservative for aqueous wood preservative treatment solution during the wet-state process used in timber treatment solutions.

Application method(s) Method: - Detailed description: — Application rate(s) and frequency Application Rate: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution Dilution (%): - Number and timing of application: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.20.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. The biocidal product is not intended to function as a wood preservative against wood destroying fungus relative to product type 8. 4.20.2. Use-specific risk mitigation measures During handling phases (mixing and loading) and cleaning phases, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The product shall not be used in a wood treatment solution to be applied to wood which may come in direct contact with food, feeding stuff and livestock animals The product can be used to preserve wood treatment solutions for the treatment of wood in use classes 1, 2 and 3 only. The product can be used in a wood treatment solution where the industrial application processes of wood treatment can be carried out within a contained area situated on impermeable hard standing with bunding to prevent run-off and a recovery system in place (e.g. sump). The product can be used in wood treatment solutions for the preservation of freshly treated timber, which after treatment is stored under shelter or on impermeable hard standing, or both, to prevent direct losses to soil, sewer or water. Any losses of wood treatment solution shall be collected for reuse or disposal.

The product can be used only in wood treatment solutions for industrial application if these cannot be released to soil, ground- and surface water or any kind of sewer and the wood treatment solutions and/or the product are collected and reused or disposed of as hazardous waste. The biocidal product can be used only in wood treatment solutions used for the treatment of objects or materials which are stored until completely dried on impermeable ground and under roof, to avoid leakage into the soil. 4.20.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.20.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.20.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.21. Use description Table 57 Use # 21 – Preservation of recirculating fluids used in textile and fiber processing, leather processing, photo-processing and fountain solution systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of recirculating fluids used in textile, fiber processing, leather processing, photo-processing and fountain solution systems C(M)IT/MIT (3:1) biocidal products are used for the preservation of textile and spinning fluids, photo processing solutions, leather process (e.g. washing and soaking treatment stages) and printing fountain solutions to control the integrity of recirculating fluid by reducing microbial contamination in the bulk solution. Application method(s) Method: - Detailed description: Manual and automated dosing. The preservation of all end-products is performed in most cases highly automated by industrial users The biocidal product is added to the central sump, basin or recirculating lines in an area with adequate mixing. Application rate(s) and frequency Application Rate: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid Dilution (%): - Number and timing of application: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid Contact time 5 days Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.21.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product.

4.21.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Liquids used in textile and fiber processing fluids must not enter surface water directly. Use product only in premises that are connected to a STP. Recirculating liquids in photoprocessing systems and fountain solution systems must not enter surface water directly. Use product only in premises that are connected to a STP. 4.21.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.21.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.21.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.22. Use description Table 58 Use # 22 – Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems. The biocidal product is used for preservation of fluids in pre- treatment processes (Cleaning treatment for grease removal and soil, degreasing Phosphating process, Rinse off tanks) paint spray booths and electrodeposition coating systems (e.g. cataphoretic baths) applied in Car Refinishing and Original equipment Car Manufacturing to control the integrity of recirculating fluid by reducing microbial contamination from bacteria and fungi in the bulk solution. Application method(s) Method: - Detailed description: — Application rate(s) and frequency

Application Rate: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. Dilution (%): - Number and timing of application: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. The biocidal product is added at the time of manufacture, storage or shipment. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.22.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.22.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.22.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.22.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.22.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.23. Use description Table 59 Use # 23 – Preservation of liquids used in closed recirculating heating systems and associated pipework Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use— Target organism(s) (including development stage) Common name: Bacteria (anaerobes and aerobes (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage:

Common name: Fungi Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in closed recirculating heating systems and associated pipework. Pre-commission biocide flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. Closed recirculating heating systems: pre-commission biocidal product flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. The biocidal product is used to control the growth of aerobic and anaerobic bacteria, fungi and biofilm in the circulating water of closed systems. Closed systems are less susceptible to corrosion, scaling and biological fouling than open systems. However microbial problems can occur, if the system is left filled and untreated. This is due to the presence of nitrite and glycols used as nutrients by microbes. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing. The feeding pipe must dose the biocidal product below the water level in order to limit the evaporation of the biocidal product. Application rate(s) and frequency Application Rate: Curative treatment - against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) - against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Preventive treatment - against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water - against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) Contact time: 24 hours against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Contact time: 48 hours Preventive treatment against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water and against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.23.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.23.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.23.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.23.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.23.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.24. Use description Table 60 Use # 24 – Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.) Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Outdoor Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.) Application method(s) Method: - Detailed description: — Application rate(s) and frequency Application Rate: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution. Dilution (%): - Number and timing of application: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L

All products should be transport and stored in a vented room. 4.24.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.24.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.24.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.24.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.24.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.25. Use description Table 61 Use # 25 – Slimicide treatment in the de-inking process of the pulp and paper Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Slimicide treatment in the de-inking process of the pulp and paper. Recycling paper /deinking paper mills. Deinking process is a manufacturing paper process of removing printing inks from waste paper-fibers to produce deinked pulp. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product is automatically dosed by pump and fixed pipes into the circuit, usually in the pulper below the water level. Application rate(s) and frequency Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated.

Dilution (%): - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.25.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.25.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.25.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.25.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.25.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.26. Use description Table 62 Use # 26 – Slimicide treatment in the wet-end stage of paper manufacturing process Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Slimicide treatment in the wet-end stage of the paper manufacturing process (paper mills, wet-end stage (water circuits), and paper mills process system).

Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Dilution (%): - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.26.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.26.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The use of C(M)IT/MIT (3:1) containing products for the slimicide treatment in the wet-end stage of the paper manufacturing process is restricted to (a) curative treatments in plants connected to a slimicide-free water from a pulp mill and only for the treatment of the short circulation of the paper mill; and (b) preventive treatments, and, for both cases, only if the factory’s waste water is purified in an on-site (full) industrial sewage treatment plant with a minimal capacity of 5000 m3 per day as described in the Industrial Emission Directive 2010/75/EU (Best Available Techniques for the production of pulp, paper and board) and if a dilution of at least 200 times in surface water is achieved after the industrial sewage treatment plant.

4.26.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.26.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.26.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.27. Use description Table 63 Use # 27 – Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF membranes Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF membranes Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Biocidal product application on a routine basis will prevent biofilm growth on Reverse Osmosis or Nano Filtration membrane surfaces, feed spacer, filter media and pipework. The biocidal product should be dispensed to the feed water at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid Dilution (%): - Number and timing of application: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.27.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.27.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information);

protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Use product only in premises that are connected to a STP. 4.27.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.27.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.27.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.28. Use description Table 64 Use # 28 – Products to control microbial deterioration in fluids used for working or cutting metal, glass or other materials Product typePT13 - Working or cutting fluid preservatives (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Products to control microbial deterioration in fluids used for working or cutting metal, glass or other materials The biocidal product is recommended to control the growth of bacteria and fungi in fluids used for metalworking fluids (cutting, grinding, rolling, drawing, etc.) metal surface treatment (aqueous multipurpose and de-watering rust cleaner fluids, etc.) and cutting fluids for glass or other materials. Application method(s) Method: - Detailed description: The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Curative treatment: When the system is noticeably fouled, apply 14,9 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Preventive treatment: When control is obtained, adding 10 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Dilution (%): - Number and timing of application: Curative treatment: When the system is noticeably fouled, apply 14,9 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Contact time: 24 h Preventive treatment: When control is obtained, adding 10 g C(M)IT/MIT (3:1) per m3 of fluid to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.28.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product.

4.28.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.28.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.28.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.28.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 5. GENERAL DIRECTIONS FOR USE Instructions for use, risk mitigation measures and other directions for use under this section are valid for any authorised uses within the meta SPC 3. OF THE META SPC 3 5.1. Instructions for use The duration of the effect is dependent on the performance requirements of the customer for their preserved material and on the specific ingredients composition and pH of the preserved product. Always read the label or leaflet before use and follow all the instructions provided. Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.) PRECAUTIONARY MEASURES DURING STORAGE AND TRANSPORT: Keep in a well-ventilated place. The product as supplied may evolve gas (largely carbon dioxide) slowly. To prevent the buildup of pressure the product is packaged in specially vented containers, where necessary. Keep this product in the original container when not in use. Container must be stored and transported in an upright position to prevent spilling the contents through the vent, where fitted. 5.2. Risk mitigation measures — 5.3. Particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment Skin contact: Remove contaminated clothing and shoes. Wash contaminated skin with water. Contact poison treatment specialist if symptoms occur. Eye contact: Immediately flush with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses if easy to do. Continue to rinse with tepid water for at least 30 minutes. Call 112/ambulance for medical assistance.

Ingestion: Wash out mouth with water. Contact poison treatment specialist. Seek medical advice immediately if symptoms occur and/or large quantities have been ingested. Do not give fluids or induce vomiting. Inhalation (of spray mist): Remove victim to fresh air and keep at rest in a position comfortable for breathing. Seek medical advice immediately if symptoms occur and/or large quantities have been inhaled. In case of impaired consciousness place in recovery position and seek medical advice immediately. Keep the container or label available. 5.4. Instructions for safe disposal of the product and its packaging Do not discharge unused product on the ground, into water courses, into pipes (e.g. sink, toilets) nor down the drains. Dispose of unused product, its packaging and all other waste, in accordance with local regulations. 5.5. Conditions of storage and shelf-life of the product under normal conditions of storage Conditions for safe storage, including any incompatibilities: Keep in a dry, cool and well-ventilated place, in the original container. Shelf-life: 12 months Protect from sunlight. Recommendation: If a metal packaging is used, a varnish layer should be applied. 6. OTHER INFORMATION — 7. THIRD INFORMATION LEVEL: INDIVIDUAL PRODUCTS IN THE META SPC 3 7.1. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ CF 400 BiocideMarket area: EUDab 4228Market area: EUBAL 400BIMarket area: EU Biocide 400Market area: EUBiotech 400Market area: EUBiocide KT400Market area: EUBioCheck KT400Market area: EUKT400Market area: EUC 412 TTMarket area: EUDab 4228Market area: EUDeep Bio® 400Market area: EUEcosafe Bio 400Market area: EUFiltralga MEMarket area: EUFiltralga 9550Market area: EUPH-SB400Market area: EUHelamin BZ9550Market area: EUIsotreat 400Market area: EUOS Isobio4Market area: EUOdysside B 330Market area: EURelvamine BIOCMarket area: EUSayvol Bio LP400Market area: EUAuthorisation numberEU-0025449-0004 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-95,9 7.2. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™CF 210 BIOCIDEMarket area: EUBAL 210BIMarket area: EUBioCheck KT210Market area: EUBiocide KT210Market area: EU Biocide 210Market area: EUBiotech 210Market area: EUB203-210Market area: EUDeep Bio® 210Market area: EUEcosafe Bio 210Market area: EUFiltralga ME-15Market area: EUKT210Market area: EUIsotreat 210Market area: EUMIRECIDE-M/86Market area: EUMK3203Market area: EUMK3094Market area: EUMK3394Market area: EUOS Isobio 210Market area: EUOdysside B 330MMarket area: EUPH-SB210Market area: EUSTENCO B-85Market area: EUSayvol Bio LP210Market area: EUTECNA 520Market area: EUAuthorisation numberEU-0025449-0005 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-93,2

7.3. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™WT 210 BIOCIDEMarket area: EUA-CID SAMarket area: EUADUR 166Market area: EUALG 200Market area: EU Biocide BALK 20Market area: EUBiocide KT210WTMarket area: EUFrance Algue 242Market area: EUKL60 TA21Market area: EUKT210WTMarket area: EUMK3094Market area: EUMK3394Market area: EUMK3203Market area: EUB203-210WTMarket area: EUBiocide 210WTMarket area: EUBiotech 210WTMarket area: EUDeep Bio® 210WTMarket area: EUEcosafe Bio 210WTMarket area: EUOS Isobio 210WTMarket area: EUPH-SB210WTMarket area: EUSayvol Bio LP210WTMarket area: EUAuthorisation numberEU-0025449-0006 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-93,2 7.4. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ WTE BIOCIDEMarket area: EUKATHON™ WTEMarket area: EUKATHON™ LXE BIOCIDEMarket area: EUKATHON™ LXEMarket area: EUKATHON™ MWE BIOCIDEMarket area: EUBansan 150Market area: EUBiocide KT200LXMarket area: EU Biocide KT200WTMarket area: EUBiocide KT200MWMarket area: EUBiocide 515WTEMarket area: EUBiocide 515 MWMarket area: EUBiotech 103WTEMarket area: EUBioCheck WTEMarket area: EUBioCheck KT MWMarket area: EUBiocheck WBMarket area: EUBiocheck 3103Market area: EUBiotech 103MWMarket area: EUBIOMATE SAN9363Market area: EUBIO 417Market area: EUB203WTEMarket area: EUB203MWMarket area: EUC 412 TTEMarket area: EUDeep Bio® 20MWMarket area: EUDeep Bio® 20WTEMarket area: EUEcosafe Bio WTEMarket area: EUEcosafe Bio MWMarket area: EUHydrex™ 7310Market area: EUIsotreat WTEMarket area: EUKT200LXMarket area: EUKT200WTMarket area: EUKT200MWMarket area: EUMIRECIDE-M/87Market area: EUNovocide 10 CMarket area: EUOBBIO210Market area: EUOS Isobio 1.5WTEMarket area: EUPastosept KMarket area: EUPH-SB102WTEMarket area: EU PH-SB102MWMarket area: EUPS 2175Market area: EUSAN ADDITIVEMarket area: EUSANY POOLMarket area: EUSayvol Bio WTEMarket area: EUSayvol Bio LP MWMarket area: EUWacozid 3150Market area: EUOS Isobio 1.5MWMarket area: EUBAC-SMarket area: EUBiocide BAL GXMarket area: EUBiocide BAL P10Market area: EUBiocide BALK 10Market area: EUbiocil-IMarket area: EUBIOMATE MBC781Market area: EUFrance Algue 222Market area: EUGEWA B 352Market area: EUHCT-B-71Market area: EUO'RIZON 415Market area: EUrascal-B-71Market area: EUWANSON W23LMarket area: EUwatERTreat BIO253 BMarket area: EUAuthorisation numberEU-0025449-0007 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,3 7.5. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ CF 150 BiocideMarket area: EUKATHON™ CF-150 BiocideMarket area: EU

KATHON™ CF-150Market area: EUAAHS BIMarket area: EUACN Green Line 802Market area: EUAQ 616Market area: EUAQF 415Market area: EUAQUATREAT 415Market area: EUATN JB48Market area: EUBAL 200BIMarket area: EUBewacid B 728Market area: EUBiocheck WB CFMarket area: EUBiocheck 3103 CFMarket area: EUBiocide 515Market area: EUBiocide KT200Market area: EUBioCheck KTMarket area: EUBIOCONTROL 5Market area: EUBIOMATE MBC781EMarket area: EUBiopleX TZ 150Market area: EUBio-Safe KT200Market area: EUBiotech 103Market area: EUB203Market area: EUBW 415Market area: EUBS4005AMarket area: EUBusan 1078Market area: EUButrol 1078Market area: EUBulab 8862Market area: EUBulab 6057Market area: EUCarillion ITAMarket area: EUCerti-KT200Market area: EUCH32Market area: EUComChem Bio ITAMarket area: EU Dab 448Market area: EUDeep Bio® 20Market area: EUDIABICIDE 90 AMarket area: EUDIPOLIQUE 156Market area: EUEcoral 1015Market area: EUEcosafe Bio WTMarket area: EUEkobio-5Market area: EUES515Market area: EUFINEALGUA MEMarket area: EUGE32Market area: EUHydrex™ 7943Market area: EUHCS B32Market area: EUIn-BoiMarket area: EUIsocil® Ultra 1.5Market area: EUIsotreatMarket area: EUIWT KT200Market area: EUKT200Market area: EULubron BD 100Market area: EULubron BD 110Market area: EULubron BD 120Market area: EUMB 215Market area: EUMikrobizid M 24Market area: EUMIRECIDE-KW/600Market area: EUMIRECIDE-KW/600.XMarket area: EUNovocide 10Market area: EUNovo Cide 10Market area: EUNW515Market area: EUOS Isobio 1.5Market area: EUPA32Market area: EUPH-SB102Market area: EU PS 2176Market area: EUQUIPROISO LGMarket area: EURAL200Market area: EURelcide 310Market area: EUSayvol Bio LPMarket area: EUST202Market area: EUStarcide Ultra 1.5Market area: EUSwiftclean BIMarket area: EUUPINZOL -10Market area: EUWacozid 3150Market area: EUWacozid 3150 CFMarket area: EUWatercare WHM KT200Market area: EUhygel KW 60 BMarket area: EUBioCheck KT200Market area: EUAuthorisation numberEU-0025449-0008 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,3 7.6. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ CG/ICP BiocideMarket area: EUKATHON™ CG-ICPMarket area: EUKATHON™ CG/ICP PreservativeMarket area: EUKATHON™ MK BiocideMarket area: EUBiocide KT200ICPMarket area: EUBiogat CG ICPMarket area: EUIsocil® HP 1.5Market area: EUMIRECIDE-KW/24Market area: EU Authorisation numberEU-0025449-0009 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,2 7.7. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ CG/ICPII BiocideMarket area: EUAuthorisation numberEU-0025449-0010 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,2

7.8. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ CL 150 BiocideMarket area: EUSPECTRUS NX1164Market area: EUAuthorisation numberEU-0025449-0011 1-3Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,2 META SPC 4

1. META SPC 4 ADMINISTRATIVE INFORMATION 1.1. Meta SPC 4 identifier Identifiermeta-SPC 4 KATHON 1.5-3.5 Na 1.2. Suffix to the authorisation number Number1-4 1.3. Product type(s) Product type(s) PT02 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants) PT04 - Food and feed area (Disinfectants) PT06 - Preservatives for products during storage (Preservatives) PT11 - Preservatives for liquid-cooling and processing systems (Preservatives) PT12 - Slimicides (Preservatives)
2. META SPC 4 COMPOSITION 2.1. Qualitative and quantitative information on the composition of the meta SPC 4 Common nameIUPAC nameFunctionCAS numberEC numberContent (%)MinMaxMixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,25,1 2.2. Type(s) of formulation of the meta SPC 4 Formulation(s)AL - Any other liquid
3. HAZARD AND PRECAUTIONARY STATEMENTS OF THE META SPC 4 Hazard statements Harmful if inhaled. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Very toxic to aquatic life with long lasting effects. Corrosive to the respiratory tract. Harmful if swallowed. Precautionary statements Do not breathe fume. Wash skin thoroughly after handling. Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Avoid release to the environment. Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. Take off contaminated clothing. And wash it before reuse. If skin irritation or rash occurs: Get medical advice. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Collect spillage. Store locked up. IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell.
4. AUTHORISED USE(S) OF THE META SPC 4 4.1. Use description Table 65 Use # 1 – Preservation of sump water in air conditioning and air washer systems Product typePT02 - Disinfectants and algaecides not intended for direct application to humans or animals (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae Development stage: Field(s) of use Outdoor Preservation of sump water in air conditioning and air washer systems. Air conditioning systems and in air washer systems to preserve the sump water. Air washer systems are used extensively in textile factories and in the tobacco industry to scrub or clean the air and for fine control of temperature and humidity. Application method(s) Method: Open and closed Systems Detailed description: Automatic and Manual Dosing The biocidal product is typically added in a central chilled water sump which supplies several air washers. The loading process may be conducted either manually or by automation. In the automated process, the biocide is metered directly into the sump from a holding tank or other type of bulk container by a dosimeter (pump). The feeding pipe must dose the biocidal product below the water level in order to limit its evaporation. Application rate(s) and frequency Application Rate: Curative application: Bacteria, yeasts and fungi. When the system is noticeably fouled, apply 5 to 14,9 mg C(M)IT/MIT (3:1) per Litre of water to be treated, as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Preventive application: algae When control is obtained, add a continuous or semi continuous feed of 3 to 5 mg C(M)IT/MIT (3:1) per L of water to be treated Dilution (%): - Number and timing of application: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 5 to 14,9 mg C(M)IT/MIT (3:1) per Litre of water to be treated, as post treatment after a shock dose of minimum 0,3 ppm of free chlorine. Contact time of 1 hour. Preventive application: algae When control is obtained, add a continuous or semi continuous feed of 3 to 5 mg C(M)IT/MIT (3:1) per L of water to be treated. Regardless of the manner of treatment, the total concentration of the active ingredient C(M)IT/MIT (3:1) in the system should not exceed 14,9 mg/L in the sump water. Preliminary steps prior to addition: The biocidal product is automatically dosed to the system. Manual handling is necessary for the loading of the biocidal product into the dosing systems. Application Frequency: Nominally every 2 to 3 days or as needed to obtain control. Repeat until fouling is reduced to an acceptable level for controlling the microbial growth. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.1.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). The CMIT/MIT biocidal products are used after a shock dose of free chlorine in this application as standard industry practice.

4.1.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.1.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.1.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.1.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.2. Use description Table 66 Use # 2 – Preservation of fluids in conveyor belts and pasteurisers Product typePT04 - Food and feed area (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Preservation of fluids in conveyor belts and pasteurisers The biocidal product is used for the preservation of process fluids in pasteurisers and conveyor belts used in food industry. The biocidal product is used in these systems to either control or kill bacteria and fungi. Application method(s) Method: Closed system Detailed description: Automated dosing The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing (e.g. collecting sump below the conveyor belt). Application rate(s) and frequency Application Rate: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 10 to 14,9 g C(M)IT/MIT (3:1) per m3 of water to be treated as post treatment after a shock dose of minimum 0,3 ppm of free chlorine Preventive application: Bacteria: When control is obtained, add a continuous or semi continuous feed of 2,5 to 5 g C(M)IT/MIT (3:1) per m3 of water to be treated. Dilution (%): - Number and timing of application: Curative application: Bacteria, yeasts and fungi When the system is noticeably fouled, apply 10 to 14,9 g C(M)IT/MIT (3:1) per m3 of water to be treated as post treatment after a shock dose of minimum 0,3 ppm of free chlorine.

Contact time of 1 hour. Preventive application: Bacteria: When control is obtained, add a continuous or semi continuous feed of 2,5 to 5 g C(M)IT/MIT (3:1) per m3 of water to be treated. Preliminary steps prior to addition: The biocidal product is automatically dosed to system. Manual handling is necessary for the loading of containers containing the biocidal product into the dosing systems. Application Frequency: Nominally every 2 to 3 days or as needed to obtain control. Repeat until fouling is reduced to an acceptable level for controlling the microbial growth. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.2.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). The CMIT/MIT biocidal products are used after a shock dose of free chlorine in this application as standard industry practice. 4.2.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.2.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.2.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.2.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.3. Use description Table 67 Use # 3 – Long term offline preservation of reverse osmosis membranes used in potable water Product typePT04 - Food and feed area (Disinfectants)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria Development stage: Field(s) of use Indoor Long term offline preservation of reverse osmosis membranes used in potable water The C(M)IT/MIT (3:1) biocidal product is recommended for controlling biological growth in off-line trains reverse osmosis membranes producing potable water for extended periods of time. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. It is recommended that fouled membranes be cleaned prior to shut-down and preservation. Please refer to RO /NF supplier manual for membrane cleaning and system shutdown procedures. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. After complete filling of the trains RO/NF systems with the biocide solution, pumps are stopped (Off line treatment) for extended periods of time. Typically C(M)IT/MIT (3:1) solutions are prepared in the CIP (cleaning in place) tank and added via the dosing system. Dilution with the permeate water or high quality water is recommended for the preparation of the biocide solution. Membranes should be soaked in the biocide solution during the shut-down period. Application rate(s) and frequency Application Rate: 7,5 -20 g of C(M)IT/MIT (3:1)/ m3 of water Dilution (%): - Number and timing of application: 7,5 -20 g of C(M)IT/MIT (3:1)/ m3 of water Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.3.1. Use-specific instructions for use Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.). Prior to taking the membranes back on-line, flush carefully the elements with permeate water in order to eliminate all the residual biocidal product. 4.3.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During mixing and loading and cleaning of the whole system, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information);

Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.3.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.3.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.3.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.4. Use description Table 68 Use # 4 – Preservation of paints and coatings Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Outdoor Preservation of paints and coatings (including electrodeposition) The biocidal product is recommended to control the growth of bacteria and yeasts in coatings applied by an electrodeposition process and associated rinse systems and in water-based paints and coatings in storage containers before use. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional paints and general public paints: 7,5-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.4.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. 4.4.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (Mixing and Loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal concentration of products from Meta SPC 1, 2, 3 and 4 to be added in paints used must be below the threshold value of 15 ppm. 4.4.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.4.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.4.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.5. Use description Table 69 Use # 5 – Preservation of fluids used in paper, textile and leather production - Curative treatment Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of fluids used in paper, textile and leather production - The biocidal product is used to reduce contamination by bacteria in textile additives (woven and non-woven, natural and synthetic including silicone emulsions) processing chemicals, all chemicals used in the leather process industry and paper additives (e.g. water pigment pastes, starch, natural gums, synthetic and natural latexes, sizing agents, coating binders, retention aids, dyes, fluorescent whitening agents, wet-strength resins) used in paper mills. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition.

Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Curative treatment: 16 to 30 mg/kg of C(M)IT/MIT (3:1) in final product Contact time: 24 hours For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.5.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.5.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of fluids used in paper, textile and leather production being above the threshold value of 15 ppm, exposure has to be limited by use of PPE protecting skin and mucous membranes potentially exposed and application of technical and organisational RMM:

Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. 4.5.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.5.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.5.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.6. Use description Table 70 Use # 6 – Preservation of glues and adhesives Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of glues and adhesives The biocidal product is recommended to control the growth of bacteria and yeasts in water-soluble and water-dispersed synthetic and natural adhesives and tackifiers in storage containers before use Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 8-30 mg/kg C(M)IT/MIT (3:1) in final product. General public uses: 8-14,9 mg/kg C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.6.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved.

It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm. 4.6.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of glues and adhesives being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.6.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.6.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.6.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.7. Use description Table 71 Use # 7 – Preservation of polymer lattices Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage:

Field(s) of use Indoor Preservation of polymer latexes The biocidal product is recommended for the control of bacteria, yeast and fungi in the manufacture, storage, and transport of latexes, synthetic polymers including Hydrolysed Poly Acryl Amide (HPAM) and biopolymers (e.g. xanthan, dextran.) natural latexes. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. To ensure uniform distribution, slowly disperse using automated metering or manual addition, into product with agitation. Mix thoroughly until evenly dispersed throughout the product. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses 14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.7.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.7.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows:

protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of polymer lattices being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.7.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.7.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.7.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.8. Use description Table 72 Use # 8 – Preservation of mineral slurries Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of mineral slurries The biocidal product is recommended to control the growth of bacteria in aqueous-based inorganic/mineral slurries and inorganic pigments which are formulated into paints, coatings and paper. Application method(s) Method: Closed system Detailed description: Manual and automated application. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 10- 30 mg/kg of C(M)IT/MIT (3:1) in final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L

HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.8.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.8.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of mineral slurries being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.8.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.8.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.8.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.9. Use description Table 73 Use # 9 – Preservation of building products applied indoor only Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of building (construction) products (including sealants, caulks, plasters etc.) The biocidal product is recommended to control the growth of bacteria in building (construction) products (sealants, caulks, biopolymers, plasters, fillers, admixtures concrete additives, joints compounds,.). Application method(s) Method: - Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products; Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at typical use rate between 16,2-30 mg C(M)IT/MIT (3:1) per Kg final product to be treated. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.9.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.9.2. Use-specific risk mitigation measures This use is restricted to the preservation of building material applied indoor only. During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area;

Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of building products being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.9.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.9.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.9.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.10. Use description Table 74 Use # 10 – Preservation of inks Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of inks The biocidal product is recommended to control the growth of bacteria and yeasts in inks and ink components (printing inks lithographic, photographic, ink-jet fluids, water based dampening or fountain solutions inks used for textile printing). The biocidal product inhibits the growth of microorganisms, which would otherwise lead to odour formation, viscosity alteration, product discolouration and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products.

Professional uses: 6-30 mg C(M)IT/MIT (3:1) /kg final product. General public uses: 6-14,9 mg C(M)IT/MIT (3:1) /kg final product. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users:- HDPE flask: 5 L (nominal)- HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)- Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L- HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.10.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed to professional users and to the general public. For products distributed to the general public the maximal concentration used must be below the threshold value of 15 ppm. 4.10.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of inks being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.10.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment

See general directions for use. 4.10.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.10.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.11. Use description Table 75 Use # 11 – Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) The biocidal product is recommended to control the growth of bacteria in functional fluids such as brake and hydraulic fluids, antifreeze additives, corrosion inhibitors, spinning fluids. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated. Dilution (%): - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.11.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.11.2. Use-specific risk mitigation measures During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The maximal products concentration used for the preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc…) being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device; Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.11.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.11.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.11.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.12. Use description Table 76 Use # 12 – Preservation of laboratory reagents Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of laboratory reagents . The biocidal product is recommended to control the growth of bacteria and yeasts in laboratory reagents. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition. Application rate(s) and frequency Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated.

Dilution (%): - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated. For the biocidal product as supplied: for industrial use only. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 1 L HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.12.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate. The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users. 4.12.2. Use-specific risk mitigation measures During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. For professional users, the maximal products concentration used for the preservation of laboratory reagents being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: Minimisation of manual phases; Use of a dosing device;

Regular cleaning of equipment and work area; Good standard of general ventilation; Training and management of staff on good practice. 4.12.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.12.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.12.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.13. Use description Table 77 Use # 13 – Offline preservation of industrial reverse osmosis membranes Product typePT06 - Preservatives for products during storage (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Offline preservation of industrial reverse osmosis membranes The biocidal product is recommended to control the growth of bacteria of reverse osmosis and nanofiltration membranes producing industrial water for extended periods of time. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to ensure adequate mixing throughout the system. After complete filling of the trains RO/NF systems with the biocide solution, pumps are stopped (Off line treatment) for extended periods of time. Typically C(M)IT/MIT (3:1) solutions are prepared in the CIP (cleaning in place) tank and added via the dosing system. Dilution with permeate water or high quality water is recommended for the preparation of the biocide solution. Membranes should be soaked in the biocide solution during the shut-down period. Application rate(s) and frequency Application Rate: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1). Dilution (%): - Number and timing of application: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1). Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.13.1. Use-specific instructions for use The preservative can be added at any stage of the production of the product. Earliest possible addition is recommended for optimal protection. Consult the manufacturer to determine the optimal dosage for the various products to be preserved. It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests. The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

4.13.2. Use-specific risk mitigation measures Rinse the system with water prior to perform the maintenance of the system. During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.13.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.13.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.13.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.14. Use description Table 78 Use # 14 – Preservation of liquids used in closed recirculating cooling systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in closed recirculating cooling systems (Closed re-circulating cooling water systems comprise compressor cooling, air conditioning chilled water, boilers, engine jacket cooling, power supply cooling, and other industrial processes). The biocidal product is used to control the growth of aerobes and anaerobes bacteria, yeast, fungi, and biofilm in the circulating water of closed systems Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative efficacy:- against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours - against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours.- against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours. Preventive efficacy:- against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. - against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water.

Dilution (%): - Number and timing of application: Curative efficacy: against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours Preventive efficacy: against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.14.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.14.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.14.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.14.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.14.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.15. Use description Table 79 Use # 15 – Preservation of liquids used in small open recirculating cooling systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage)

Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae (green algae and cyanobacteria) Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in small open recirculating cooling systems (blowdown and recirculating flow rates, as well as total volume of water limited to 2 m3/h, and 100 m3/h and 300 m3 respectively) Process and cooling water: Used to control the growth of bacteria, algae, fungi and biofilm Application method(s) Method: Open system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative treatment Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water, - against biofilm (including L. pneumophila) at 1,5 to 14,9 g C(M)IT/MIT (3:1) / m3 of water, - against fungi (including yeast) at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: - against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, - against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. Preventive treatment: against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.15.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.15.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation;

Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Cooling fluid must not enter surface water directly. Use product only in premises that are connected to a STP. The product can only be used when the cooling towers are equipped with drift eliminators that reduce the drift at least by 99 %. 4.15.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.15.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.15.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.16. Use description Table 80 Use # 16 – Preservation of liquids used in pasteurizers, conveyor belts and air washers Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Common name: Algae (green algae and cyanobacteria) Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in non-food pasteurizers and conveyor belts, air washers. Application method(s) Method: - Detailed description: The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing (e.g. collecting sump below the conveyor belt). The feeding pipe is used to dose the biocidal product below the water level in order to limit its evaporation. Application rate(s) and frequency Application Rate: Curative treatment: -against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water

Contact time: 48 hours. Preventive treatment: Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.16.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. Air washers: For use only in industrial air-washer systems that maintain effective mist eliminating components. 4.16.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.16.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.16.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.16.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.17. Use description Table 81 Use # 17 – Preservation of wood treatment solutions Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Scientific name: fungi Common name: other Development stage: Field(s) of use Indoor Outdoor Preservation of wood treatment solutions for application on wood of classes 1, 2 and 3 only. The biocidal product is used as a preservative for aqueous wood preservative treatment solution during the wet-state process used in timber treatment solutions.

Application method(s) Method: - Detailed description: — Application rate(s) and frequency Application Rate: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution Dilution (%): - Number and timing of application: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.17.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. The biocidal product is not intended to function as a wood preservative against wood destroying fungus relative to product type 8. 4.17.2. Use-specific risk mitigation measures During handling phases (mixing and loading) and cleaning phases, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The product shall not be used in a wood treatment solution to be applied to wood which may come in direct contact with food, feeding stuff and livestock animals The product can be used to preserve wood treatment solutions for the treatment of wood in use classes 1, 2 and 3 only. The product can be used in a wood treatment solution where the industrial application processes of wood treatment can be carried out within a contained area situated on impermeable hard standing with bunding to prevent run-off and a recovery system in place (e.g. sump). The product can be used in wood treatment solutions for the preservation of freshly treated timber, which after treatment is stored under shelter or on impermeable hard standing, or both, to prevent direct losses to soil, sewer or water. Any losses of wood treatment solution shall be collected for reuse or disposal.

The product can be used only in wood treatment solutions for industrial application if these cannot be released to soil, ground- and surface water or any kind of sewer and the wood treatment solutions and/or the product are collected and reused or disposed of as hazardous waste. The biocidal product can be used only in wood treatment solutions used for the treatment of objects or materials which are stored until completely dried on impermeable ground and under roof, to avoid leakage into the soil. 4.17.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.17.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.17.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.18. Use description Table 82 Use # 18 – Preservation of recirculating fluids used in textile and fiber processing, leather processing, photo-processing and fountain solution systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preservation of recirculating fluids used in textile, fiber processing, leather processing, photo-processing and fountain solution systems C(M)IT/MIT (3:1) biocidal products are used for the preservation of textile and spinning fluids, photo processing solutions, leather process (e.g. washing and soaking treatment stages) and printing fountain solutions to control the integrity of recirculating fluid by reducing microbial contamination in the bulk solution. Application method(s) Method: - Detailed description: Manual and automated dosing. The preservation of all end-products is performed in most cases highly automated by industrial users The biocidal product is added to the central sump, basin or recirculating lines in an area with adequate mixing. Application rate(s) and frequency Application Rate: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid Dilution (%): - Number and timing of application: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid Contact time 5 days Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.18.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product.

4.18.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Liquids used in textile and fiber processing fluids must not enter surface water directly. Use product only in premises that are connected to a STP. Recirculating liquids in photoprocessing systems and fountain solution systems must not enter surface water directly. Use product only in premises that are connected to a STP. 4.18.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.18.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.18.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.19. Use description Table 83 Use # 19 – Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Field(s) of use Indoor Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems. The biocidal product is used for preservation of fluids in pre- treatment processes (Cleaning treatment for grease removal and soil, degreasing Phosphating process, Rinse off tanks) paint spray booths and electrodeposition coating systems (e.g. cataphoretic baths) applied in Car Refinishing and Original equipment Car Manufacturing to control the integrity of recirculating fluid by reducing microbial contamination from bacteria and fungi in the bulk solution. Application method(s) Method: - Detailed description: — Application rate(s) and frequency

Application Rate: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. Dilution (%): - Number and timing of application: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. The biocidal product is added at the time of manufacture, storage or shipment. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.19.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.19.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.19.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.19.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.19.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.20. Use description Table 84 Use # 20 – Preservation of liquids used in closed recirculating heating systems and associated pipework Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use— Target organism(s) (including development stage) Common name: Bacteria (anaerobes and aerobes (including Legionella pneumophila) Development stage: Common name: Yeasts Development stage:

Common name: Fungi Development stage: Field(s) of use Indoor Outdoor Preservation of liquids used in closed recirculating heating systems and associated pipework. Pre-commission biocide flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. Closed recirculating heating systems: pre-commission biocidal product flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. The biocidal product is used to control the growth of aerobic and anaerobic bacteria, fungi and biofilm in the circulating water of closed systems. Closed systems are less susceptible to corrosion, scaling and biological fouling than open systems. However microbial problems can occur, if the system is left filled and untreated. This is due to the presence of nitrite and glycols used as nutrients by microbes. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing. The feeding pipe must dose the biocidal product below the water level in order to limit the evaporation of the biocidal product. Application rate(s) and frequency Application Rate: Curative treatment - against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) - against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Preventive treatment - against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water - against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water. Dilution (%): - Number and timing of application: Curative treatment: against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) Contact time: 24 hours against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Contact time: 48 hours Preventive treatment against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water and against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.20.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.20.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.20.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.20.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.20.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.21. Use description Table 85 Use # 21 – Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.) Product typePT11 - Preservatives for liquid-cooling and processing systems (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Outdoor Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.) Application method(s) Method: - Detailed description: — Application rate(s) and frequency Application Rate: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution. Dilution (%): - Number and timing of application: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution. Category(ies) of usersIndustrial Pack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L

All products should be transport and stored in a vented room. 4.21.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.21.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.21.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.21.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.21.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.22. Use description Table 86 Use # 22 – Slimicide treatment in the de-inking process of the pulp and paper Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Slimicide treatment in the de-inking process of the pulp and paper. Recycling paper /deinking paper mills. Deinking process is a manufacturing paper process of removing printing inks from waste paper-fibers to produce deinked pulp. Application method(s) Method: Closed system Detailed description: Manual and automated dosing. The biocidal product is automatically dosed by pump and fixed pipes into the circuit, usually in the pulper below the water level. Application rate(s) and frequency Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated.

Dilution (%): - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.22.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.22.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. 4.22.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.22.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.22.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.23. Use description Table 87 Use # 23 – Slimicide treatment in the wet-end stage of paper manufacturing process Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Common name: Yeasts Development stage: Common name: Fungi Development stage: Field(s) of use Indoor Slimicide treatment in the wet-end stage of the paper manufacturing process (paper mills, wet-end stage (water circuits), and paper mills process system).

Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Application rate(s) and frequency Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Dilution (%): - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.23.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.23.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. The use of C(M)IT/MIT (3:1) containing products for the slimicide treatment in the wet-end stage of the paper manufacturing process is restricted to (a) curative treatments in plants connected to a slimicide-free water from a pulp mill and only for the treatment of the short circulation of the paper mill; and (b) preventive treatments, and, for both cases, only if the factory’s waste water is purified in an on-site (full) industrial sewage treatment plant with a minimal capacity of 5000 m3 per day as described in the Industrial Emission Directive 2010/75/EU (Best Available Techniques for the production of pulp, paper and board) and if a dilution of at least 200 times in surface water is achieved after the industrial sewage treatment plant.

4.23.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.23.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.23.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 4.24. Use description Table 88 Use # 24 – Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF membranes Product typePT12 - Slimicides (Preservatives)Where relevant, an exact description of the authorised use—Target organism(s) (including development stage) Common name: Bacteria Development stage: Field(s) of use Indoor Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF membranes Application method(s) Method: Closed system Detailed description: Manual and automated dosing. Biocidal product application on a routine basis will prevent biofilm growth on Reverse Osmosis or Nano Filtration membrane surfaces, feed spacer, filter media and pipework. The biocidal product should be dispensed to the feed water at a point to assure adequate mixing throughout the system. Application rate(s) and frequency Application Rate: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid Dilution (%): - Number and timing of application: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid Category(ies) of usersIndustrialPack sizes and packaging material For industrial and professional users: HDPE flask: 5 L (nominal) HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) Box with HDPE liner: 20 L HDPE Drum: 110 L, 120 L, 200 L, 260 L HDPE IBC: 650 L, 800 L, 1000 L, 1250 L All products should be transport and stored in a vented room. 4.24.1. Use-specific instructions for use Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product. 4.24.2. Use-specific risk mitigation measures Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step. During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: Minimisation of manual phases (process automation); Use of a dosing device; Regular cleaning of equipment and work area; Avoidance of contact with contaminated tools and objects; Good standard of general ventilation; Training and management of staff on good practice. PPE is as follows: protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information);

protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); Eye protection; Substance/task appropriate respirator if ventilation is inadequate. Use product only in premises that are connected to a STP. 4.24.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment See general directions for use. 4.24.4. Where specific to the use, the instructions for safe disposal of the product and its packaging See general directions for use. 4.24.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage See general directions for use. 5. GENERAL DIRECTIONS FOR USE Instructions for use, risk mitigation measures and other directions for use under this section are valid for any authorised uses within the meta SPC 4. OF THE META SPC 4 5.1. Instructions for use The duration of the effect is dependent on the performance requirements of the customer for their preserved material and on the specific ingredients composition and pH of the preserved product. Always read the label or leaflet before use and follow all the instructions provided. Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.) PRECAUTIONARY MEASURES DURING STORAGE AND TRANSPORT: Keep in a well-ventilated place. The product as supplied may evolve gas (largely carbon dioxide) slowly. To prevent the buildup of pressure the product is packaged in specially vented containers, where necessary. Keep this product in the original container when not in use. Container must be stored and transported in an upright position to prevent spilling the contents through the vent, where fitted. 5.2. Risk mitigation measures — 5.3. Particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect the environment Skin contact: Remove contaminated clothing and shoes. Wash contaminated skin with water. Contact poison treatment specialist if symptoms occur. Eye contact: Immediately flush with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses if easy to do. Continue to rinse with tepid water for at least 30 minutes. Call 112/ambulance for medical assistance. Ingestion: Wash out mouth with water. Contact poison treatment specialist. Seek medical advice immediately if symptoms occur and/or large quantities have been ingested. Do not give fluids or induce vomiting. Inhalation (of spray mist): Remove victim to fresh air and keep at rest in a position comfortable for breathing. Seek medical advice immediately if symptoms occur and/or large quantities have been inhaled. In case of impaired consciousness place in recovery position and seek medical advice immediately. Keep the container or label available.

5.4. Instructions for safe disposal of the product and its packaging Do not discharge unused product on the ground, into water courses, into pipes (e.g. sink, toilets) nor down the drains. Dispose of unused product, its packaging and all other waste, in accordance with local regulations. 5.5. Conditions of storage and shelf-life of the product under normal conditions of storage Conditions for safe storage, including any incompatibilities: Keep in a dry, cool and well-ventilated place, in the original container. Shelf-life: 24 months Protect from sunlight. Recommendation: If a metal packaging is used, a varnish layer should be applied. 6. OTHER INFORMATION — 7. THIRD INFORMATION LEVEL: INDIVIDUAL PRODUCTS IN THE META SPC 4 7.1. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ LX 300 BIOCIDEMarket area: EUKATHON™ WT 300 BiocideMarket area: EUACQ 819Market area: EUBiocide KT300WTMarket area: EUKT300WTMarket area: EU KT300LXMarket area: EUSANITER 454Market area: EUOS Isobio3Market area: EUAuthorisation numberEU-0025449-0012 1-4Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-94,6 7.2. Trade name(s), authorisation number and specific composition of each individual product Trade name(s)KATHON™ WT 150 BiocideMarket area: EUKATHON™ LX 150 BIOCIDEMarket area: EUBIO 419Market area: EUSANITER 420Market area: EUAuthorisation numberEU-0025449-0013 1-4Common nameIUPAC nameFunctionCAS numberEC numberContent (%)Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6) (Mixture of CMIT/MIT)Active Substance55965-84-92,3